性别比与受孕时间：四项大型欧洲人口调查分析
Sex ratio and time to pregnancy: analysis of four large European population surveys.
作者信息
Joffe Mike, Bennett James, Best Nicky, Jensen Tina Kold
机构信息
Department of Epidemiology and Public Health, Imperial College, London W2 1PG.
出版信息
BMJ. 2007 Mar 10;334(7592):524. doi: 10.1136/bmj.39097.508426.BE. Epub 2007 Feb 2.
OBJECTIVE
To test whether the secondary sex ratio (proportion of male births) is associated with time to pregnancy, a marker of fertility. Design Analysis of four large population surveys. Setting Denmark and the United Kingdom. Participants 49 506 pregnancies.
MAIN OUTCOME MEASURE
Secondary sex ratio.
RESULTS
No association was found between the sex ratio and time to pregnancy and no discernible trend was found for sex ratio with time to pregnancy, either within individual datasets or in the pooled analysis. The odds ratios were 0.97 (95% confidence interval 0.90 to 1.04) for contraceptive failures, 1.01 (0.96 to 1.05) for time to pregnancy of 2-4 months, 1.02 (0.97 to 1.08) for 5-10 months, 0.98 (0.93 to 1.03) for 11 months or more, and 0.88 (0.74 to 1.06) for fertility treatment, with 0-1 months as the reference category.
CONCLUSION
No association was found between the secondary sex ratio and time to pregnancy.
目的
检验第二性征比例（男婴出生比例）是否与受孕时间（生育能力的一个指标）相关。设计对四项大型人口调查进行分析。地点丹麦和英国。参与者49506例妊娠。
主要观察指标
第二性征比例。
结果
在个体数据集内或汇总分析中，均未发现性别比例与受孕时间之间存在关联，也未发现性别比例随受孕时间有明显趋势。以0 - 1个月为参照类别，避孕失败的比值比为0.97（95%置信区间0.90至1.04），受孕时间为2 - 4个月的比值比为1.01（0.96至1.05），5 - 10个月的比值比为1.02（0.97至1.08），11个月及以上的比值比为0.98（0.93至1.03），接受生育治疗的比值比为0.88（0.74至1.06）。
结论
未发现第二性征比例与受孕时间之间存在关联。
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