Della Santina Charles, Migliaccio Americo, Patel Amit
Departments of Otolaryngology-Head & Neck Surgery and Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Conf Proc IEEE Eng Med Biol Soc. 2005;2005:7380-5. doi: 10.1109/IEMBS.2005.1616217.
Patients who fail to compensate for bilateral loss of vestibular sensory function are disabled by disequilibrium and illusory movement of the visual field during head movement. An implantable prosthesis that restores vestibular sensation could significantly improve quality of life for these patients. To be effective, such a device should encode head rotation in all 3 dimensions. We describe the 3-dimensional angular vestibulo-ocular reflex of normal chinchillas and vestibular-deficient chinchillas undergoing functional electrical stimulation of the vestibular nerve. We also describe the design and fabrication of a head-mounted, 8 electrode vestibular prosthesis that encodes head movement in 3 dimensions.
未能代偿双侧前庭感觉功能丧失的患者会因头部运动时的平衡失调和视野的虚幻运动而致残。一种能够恢复前庭感觉的可植入假体可以显著改善这些患者的生活质量。要想有效，这样的装置应能对三维空间中的头部旋转进行编码。我们描述了正常龙猫以及接受前庭神经功能性电刺激的前庭功能缺失龙猫的三维角前庭眼反射。我们还描述了一种头戴式八电极前庭假体的设计与制造，该假体能够对三维空间中的头部运动进行编码。
