Parsons Jeffrey T, Rosof Elana, Mustanski Brian
Hunter College and the Graduate Center of the City University of New York, NY 10021, USA.
J Health Psychol. 2007 Mar;12(2):357-70. doi: 10.1177/1359105307074298.
The study explored the relationship between HIV medication adherence and alcohol, cognitive, social and affective factors in 272 persons with alcohol problems. Alcohol and cognitive factors significantly differentiated those who did and did not adhere. Specifically, adherence confidence and number of drinks emerged as subfactors driving the associations to adherence. Among those who were less than perfectly adherent (n = 154), only alcohol factors predicted levels of nonadherence. Cognitive factors play a role in understanding some of the differences between those who do and do not adhere to their HIV medications, but they do not differentiate among levels of nonadherence.
该研究探讨了272名有酒精问题的人在抗逆转录病毒药物依从性与酒精、认知、社会和情感因素之间的关系。酒精和认知因素显著区分了坚持服药和未坚持服药的人群。具体而言,坚持服药的信心和饮酒量是促使与坚持服药产生关联的子因素。在依从性欠佳的人群(n = 154)中,只有酒精因素能够预测不依从的程度。认知因素在理解坚持服药和未坚持服药人群之间的一些差异方面发挥作用,但它们无法区分不同程度的不依从情况。