Theodossiadis Panagiotis G, Grigoropoulos Vlassis G, Emfietzoglou John, Theodossiadis George P
Department of Ophthalmology, Athens University, 13 Lykiou Street, 106 74 Athens, Greece.
Graefes Arch Clin Exp Ophthalmol. 2007 Sep;245(9):1311-8. doi: 10.1007/s00417-007-0534-4. Epub 2007 Feb 7.
To assess vitreous findings in optic disc pit maculopathy using Optical Coherence Tomography (OCT).
Thirty-eight eyes of 38 patients (14-51 years of age) with macular detachment associated with optic disc pit maculopathy were included in the study. The patients were divided into two groups. In group 1, 16 eyes were studied by OCT at presentation and after surgical treatment. In group 2, 22 eyes were examined by OCT only after treatment. In both groups thorough vitreous examination was performed over the macula and the optic disc. All patients were operated by the macular buckling procedure.
Vitreous abnormalities were found in 28 out of 38 eyes (74%) of both groups. In group 1, 10 of the 16 eyes had vitreous traction on the macula at presentation. The traction started from the optic disc and terminated to the macula. The posterior hyaloid that exerted the traction between the points of adhesion at the optic disc and the macula had a course parallel to the retinal surface in 9 of the 10 cases. Postoperatively, vitreous traction on the macula was not found. Of the remaining 6 eyes 4 had complete or partial posterior vitreous detachment. In group 2, 8 eyes had vitreous strands over the optic disc and 5 eyes posterior vitreous detachment. In the remaining 9 cases no vitreous involvement was noticed.
OCT was able to detect vitreous abnormalities such as vitreomacular traction, vitreous strands over the optic disc and complete or partial posterior vitreous detachment associated with optic disc pit maculopathy. Our observations support the view that the abnormal vitreous over the macula and optic disc is likely to play a role in the development of macular elevation in cases with optic disc pit. Prospective OCT studies could further assist to better understand the role of vitreous in this disease.
使用光学相干断层扫描（OCT）评估视盘小凹黄斑病变的玻璃体表现。
本研究纳入38例（年龄14 - 51岁）患有与视盘小凹黄斑病变相关的黄斑脱离患者的38只眼。患者分为两组。在第1组中，16只眼在初诊时及手术治疗后接受OCT检查。在第2组中，22只眼仅在治疗后接受OCT检查。两组均对黄斑和视盘进行了全面的玻璃体检查。所有患者均接受黄斑扣带手术。
两组38只眼中的28只（74%）发现玻璃体异常。在第1组中，16只眼中有10只在初诊时黄斑存在玻璃体牵拉。牵拉起始于视盘并终止于黄斑。在10例中有9例，在视盘和黄斑粘连点之间产生牵拉的后玻璃体膜在视网膜表面平行走行。术后，未发现黄斑的玻璃体牵拉。其余6只眼中，4只存在完全或部分玻璃体后脱离。在第2组中，8只眼视盘上有玻璃体条索，5只眼有玻璃体后脱离。其余9例未发现玻璃体受累。
OCT能够检测到与视盘小凹黄斑病变相关的玻璃体异常，如玻璃体黄斑牵拉、视盘上的玻璃体条索以及完全或部分玻璃体后脱离。我们的观察结果支持这样的观点，即在视盘小凹病例中，黄斑和视盘上方的异常玻璃体可能在黄斑隆起的发展中起作用。前瞻性OCT研究可能有助于进一步更好地理解玻璃体在这种疾病中的作用。
