角膜基质透镜移植治疗先天性视盘陷窝黄斑病变：病例报告及文献复习。
Corneal stromal lenticule transplantation for the treatment of congenital optic disc pit maculopathy : a case report and review.
机构信息
Fundus Disease Department, Mianyang Wanjiang Eye Hospital, Mianyang, 621000, Sichuan, China.
出版信息
BMC Ophthalmol. 2024 Oct 4;24(1):432. doi: 10.1186/s12886-024-03707-z.
BACKGROUND
Congenital optic disc pit (ODP) is a relatively uncommon congenital anomaly of the optic disc, which seriously affects the patient's vision when combined with optic disc pit maculopathy(ODP-M). Currently, the treatment of ODP-M remains a clinical challenge and a focus of research.
CASE PRESENTATION
A boy had a pit in the inferotemporal segment of the optic disc with ODP-M. Optical Coherence Tomography(OCT) showed ODP and serous retinal detachment. He was treated with pars plana vitrectomy(PPV), followed by Corneal Stromal Lenticule (CSL) sealing and C3F8 tamponade. In the end, significant anatomical improvement was achieved, and the Best Corrected Visual Acuity(BCVA) was improved.
CONCLUSIONS
The CSL transplantation may be a viable therapeutic option for improving ODP-M with stable anatomical and functional result. However, more cases and longer follow-up are needed to confirm the safety and effectiveness of the technology.
背景
先天性视盘小凹（ODP）是一种相对少见的视盘先天性异常，当与视盘小凹伴黄斑病变（ODP-M）同时存在时，严重影响患者的视力。目前，ODP-M 的治疗仍然是临床挑战和研究的重点。
病例介绍
一名男孩的视盘颞下节有小凹，伴有 ODP-M。光学相干断层扫描（OCT）显示 ODP 和浆液性视网膜脱离。他接受了经睫状体平坦部玻璃体切除术（PPV）治疗，随后进行角膜基质透镜（CSL）密封和 C3F8 眼内填充。最终，获得了显著的解剖学改善，最佳矫正视力（BCVA）得到了提高。
结论
CSL 移植可能是改善 ODP-M 的一种可行的治疗选择，可以获得稳定的解剖学和功能结果。然而，需要更多的病例和更长的随访时间来确认该技术的安全性和有效性。
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