Xu Lin, Li Song-feng, Deng Qiong-ying, Zhou Li-ning, Gong Ji-chun, Xu Rui
Department of Anatomy, Guangxi Medical University, Nanning, Guangxi, 530021 PR China.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Feb;24(1):97-100.
To study the genetic polymorphism of 15 short tandem repeat (STR) (D2S1338ì D3S1358ì D5S818ì D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, CSF1PO, TPOX, TH01, vWA, FGA) in Maonan minority of Guangxi province.
The allele frequencies and the genotype of 15 STR loci were analyzed in 143 unrelated individuals in Maonan minority of Guangxi by PCR-STR and genescan.
There were 130 STR alleles and 390 genotypes in the 15 STR of Maonan minority, with allele frequencies ranging from 0.0035 to 0.5385. The average heterozygosity was 0.7697, the discrimination power was higher than 0.8 except for that of TPOX, the accumulative discrimination power was more than 0.999999999, and the probability of paternity exclusion was more than 0.99999918.
The 15 STR loci of Maonan minority in Guangxi possesses the characteristics of high genetic diversity, except for the TPOX locus. They can be employed in minority genetics investigation, individual and paternity test in forensic medicine.
研究广西毛南族15个短串联重复序列（STR）（D2S1338、D3S1358、D5S818、D7S820、D8S1179、D13S317、D16S539、D18S51、D19S433、D21S11、CSF1PO、TPOX、TH01、vWA、FGA）的基因多态性。
采用聚合酶链反应-STR（PCR-STR）及基因扫描技术，对广西毛南族143名无关个体的15个STR基因座的等位基因频率及基因型进行分析。
广西毛南族15个STR基因座共检出130个等位基因和390种基因型，等位基因频率范围为0.0035至0.5385。平均杂合度为0.7697，除TPOX基因座外，鉴别力均高于0.8，累积鉴别力大于0.999999999，非父排除率大于0.99999918。
广西毛南族15个STR基因座除TPOX基因座外，具有高度的遗传多样性特征，可用于少数民族遗传学研究、法医学个体识别及亲子鉴定。
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