Schulz H, Dirlich G, Zulley J
Pflugers Arch. 1975 Jul 28;358(3):203-12. doi: 10.1007/BF00587217.
The periodic alternation between REM and NREM sleep was analyzed. Usually, sleep records of consecutive nights of a subject are regarded to be independent events. However, it may be that consecutive nights are realizations of a continuously ongoing rhythm. This was tested in the present study. The temporal patterns of REM and NREM sleep in sequences of about 30 consecutive nights for 3 subjects were analyzed. The results show that only the onset of the first REM sleep phase during any one night may be predicted from the sleep onset time, whereas a systematic phase shift between consecutive nights was observed in the later REM sleep phases. Thus, the onset of later REM sleep phases is better predicted by assuming a rhythm with stable period length which controls the appearance of REM sleep phases in successive nights. Under the experimental conditions the phase shift was between 5 and 10 min per 24 hrs for the 3 subjects. The result is accordance with Kleitman's basic rest activity cycle (BRAC) hypothesis.
对快速眼动（REM）睡眠和非快速眼动（NREM）睡眠之间的周期性交替进行了分析。通常，一个受试者连续几晚的睡眠记录被视为独立事件。然而，连续的夜晚可能是持续存在的节律的表现。本研究对此进行了测试。分析了3名受试者约30个连续夜晚的快速眼动睡眠和非快速眼动睡眠的时间模式。结果表明，仅能根据入睡时间预测任何一晚第一个快速眼动睡眠阶段的开始时间，而在随后的快速眼动睡眠阶段观察到连续夜晚之间存在系统性的相位偏移。因此，通过假设具有稳定周期长度的节律来更好地预测随后快速眼动睡眠阶段的开始时间，该节律控制着连续夜晚快速眼动睡眠阶段的出现。在实验条件下，3名受试者的相位偏移为每24小时5至10分钟。该结果与克莱特曼的基本休息活动周期（BRAC）假说一致。
