• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

玻璃体内单次注射贝伐单抗后,继发于视网膜分支静脉阻塞的广泛视网膜玻璃体新生血管迅速消退。

Rapid regression of extensive retinovitreal neovascularization secondary to branch retinal vein occlusion after a single intravitreal injection of bevacizumab.

作者信息

Ahmadieh Hamid, Moradian Siamak, Malihi Mohsen

机构信息

Department of Ophthalmology, Ophthalmic Research Center, Labbafinejad Medical Center, Shaheed Beheshti Medical University, Boostan 9 St., Pasdaran Ave., Tehran, 16666, Iran.

出版信息

Int Ophthalmol. 2005 Aug-Oct;26(4-5):191-3. doi: 10.1007/s10792-007-9036-y. Epub 2007 Feb 8.

DOI:10.1007/s10792-007-9036-y
PMID:17286185
Abstract

PURPOSE

To report the rapid regression of extensive retinovitreal neovascularization following the administration of a single dose of intravitreal bevacizumab.

METHODS

A 60-year-old woman presented with recurrent vitreous hemorrhage originating from active retinovitreal neovascularization secondary to branch retinal vein occlusion. The neovascular tissue remained active despite multiple sessions of laser therapy. Intravitreal injection of 1.25 mg bevacizumab was performed.

RESULTS

Rapid regression of the retinovitreal neovascularization, a marked reduction in retinal vein engorgement, and visual improvement was observed 1 week after the intervention

CONCLUSION

Intravitreal bevacizumab can result in the rapid and dramatic regression of retinovitreal neovascularization refractory to previous laser photocoagulation.

摘要

目的

报告单次玻璃体内注射贝伐单抗后广泛视网膜玻璃体新生血管的快速消退情况。

方法

一名60岁女性因视网膜分支静脉阻塞继发的活跃视网膜玻璃体新生血管导致反复玻璃体积血就诊。尽管进行了多次激光治疗,新生血管组织仍很活跃。进行了1.25毫克贝伐单抗的玻璃体内注射。

结果

干预后1周观察到视网膜玻璃体新生血管快速消退、视网膜静脉充血明显减轻以及视力改善。

结论

玻璃体内注射贝伐单抗可使先前激光光凝治疗无效的视网膜玻璃体新生血管快速且显著消退。

相似文献

1
Rapid regression of extensive retinovitreal neovascularization secondary to branch retinal vein occlusion after a single intravitreal injection of bevacizumab.玻璃体内单次注射贝伐单抗后,继发于视网膜分支静脉阻塞的广泛视网膜玻璃体新生血管迅速消退。
Int Ophthalmol. 2005 Aug-Oct;26(4-5):191-3. doi: 10.1007/s10792-007-9036-y. Epub 2007 Feb 8.
2
Rapid improvement of retinal and iris neovascularization after a single intravitreal bevacizumab injection in a patient with central retinal vein occlusion and neovascular glaucoma.在一名患有视网膜中央静脉阻塞和新生血管性青光眼的患者中,单次玻璃体内注射贝伐单抗后视网膜和虹膜新生血管迅速改善。
Int Ophthalmol. 2008 Feb;28(1):59-61. doi: 10.1007/s10792-007-9105-2. Epub 2007 Jul 4.
3
Intravitreal bevacizumab (Avastin) as a treatment of the neovascular complications of laser-induced chorioretinal anastomosis for nonischaemic central retinal vein occlusion.玻璃体内注射贝伐单抗(阿瓦斯汀)治疗非缺血性视网膜中央静脉阻塞激光诱导脉络膜视网膜吻合术后的新生血管并发症
Clin Exp Ophthalmol. 2009 Jul;37(5):485-9. doi: 10.1111/j.1442-9071.2009.02063.x.
4
Rapid regression of retinal neovascularization following intravitreal bevacizumab in branch retinal vein occlusion imaged by optical coherence tomography angiography.玻璃体内注射贝伐单抗后视网膜分支静脉阻塞患者视网膜新生血管的快速消退:光学相干断层扫描血管造影成像研究
Indian J Ophthalmol. 2018 Apr;66(4):572. doi: 10.4103/ijo.IJO_868_17.
5
Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy.玻璃体内注射贝伐单抗(阿瓦斯汀)治疗增殖性糖尿病视网膜病变。
Ophthalmology. 2006 Oct;113(10):1695.e1-15. doi: 10.1016/j.ophtha.2006.05.064.
6
Intravitreal injection of bevacizumab for macular edema secondary to branch retinal vein occlusion:results after 12 months and multiple regression analysis.玻璃体内注射贝伐单抗治疗视网膜分支静脉阻塞继发黄斑水肿:12 个月后的结果和多元回归分析。
Retina. 2009 Oct;29(9):1242-8. doi: 10.1097/IAE.0b013e3181aa8e20.
7
Combined intravitreal bevacizumab and triamcinolone injection in a child with Coats disease.玻璃体内联合注射贝伐单抗和曲安奈德治疗一名患有科茨病的儿童。
J AAPOS. 2008 Jun;12(3):309-11. doi: 10.1016/j.jaapos.2008.01.009.
8
Comparison of two doses of intravitreal bevacizumab (Avastin) for treatment of macular edema secondary to branch retinal vein occlusion: results from the Pan-American Collaborative Retina Study Group at 6 months of follow-up.两种剂量玻璃体内注射贝伐单抗(阿瓦斯汀)治疗视网膜分支静脉阻塞继发黄斑水肿的比较:泛美视网膜协作研究组6个月随访结果
Retina. 2008 Feb;28(2):212-9. doi: 10.1097/IAE.0b013e3181619bee.
9
The effects of intravitreal bevacizumab on patients with macular edema secondary to branch retinal vein occlusion.玻璃体内注射贝伐单抗对视网膜分支静脉阻塞继发黄斑水肿患者的影响。
Can J Ophthalmol. 2009 Apr;44(2):154-9. doi: 10.3129/i09-040.
10
Intravitreal bevacizumab (Avastin) for subretinal neovascularization secondary to type 2A idiopathic juxtafoveal telangiectasia.玻璃体内注射贝伐单抗(阿瓦斯汀)治疗2A型特发性黄斑旁毛细血管扩张继发的视网膜下新生血管形成。
Graefes Arch Clin Exp Ophthalmol. 2007 Dec;245(12):1825-9. doi: 10.1007/s00417-007-0567-8. Epub 2007 Mar 8.

引用本文的文献

1
Real-Life Data of Patients with Exudative Age-Related Macular Degeneration.渗出性年龄相关性黄斑变性患者的真实世界数据。
Beyoglu Eye J. 2021 Dec 17;6(4):304-308. doi: 10.14744/bej.2021.63496. eCollection 2021.
2
The adjunctive use of pre-operative intravitreal bevacizumab in the setting of proliferative diabetic retinopathy.术前玻璃体内注射贝伐单抗在增殖性糖尿病视网膜病变中的辅助应用。
Saudi J Ophthalmol. 2016 Oct-Dec;30(4):217-220. doi: 10.1016/j.sjopt.2016.10.001. Epub 2016 Oct 29.
3
Effect of Bevacizumab Injection before Vitrectomy on Intravitreal Hemorrhage in Pseudophakic Patients with Proliferative Diabetic Retinopathy.

本文引用的文献

1
Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration.玻璃体内注射贝伐单抗(阿瓦斯汀)治疗新生血管性年龄相关性黄斑变性。
Ophthalmology. 2006 Mar;113(3):363-372.e5. doi: 10.1016/j.ophtha.2005.11.019. Epub 2006 Feb 3.
2
Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals.糖尿病患者接受培加他尼(Macugen)治疗后视网膜新生血管的变化。
Ophthalmology. 2006 Jan;113(1):23-8. doi: 10.1016/j.ophtha.2005.10.012. Epub 2005 Dec 15.
3
The role of vascular endothelial growth factor in ocular health and disease.
玻璃体切割术前注射贝伐单抗对假晶状体增殖性糖尿病视网膜病变患者玻璃体积血的影响。
Ophthalmol Eye Dis. 2013 Jul 15;5:11-5. doi: 10.4137/OED.S12352. Print 2013.
4
Evaluation of ultrasound-assisted thrombolysis using custom liposomes in a model of retinal vein occlusion.评估超声辅助溶栓治疗视网膜静脉阻塞模型中定制脂质体的效果。
Invest Ophthalmol Vis Sci. 2012 Oct 5;53(11):6920-7. doi: 10.1167/iovs.12-10389.
5
Effect of intravitreal bevacizumab injection before vitrectomy on proliferative diabetic retinopathy.玻璃体切割术前玻璃体腔内注射贝伐单抗对增殖性糖尿病视网膜病变的影响。
Int J Ophthalmol. 2010;3(3):261-3. doi: 10.3980/j.issn.2222-3959.2010.03.19. Epub 2010 Sep 18.
6
Role of intravitreal bevacizumab in the management of Eales' disease.玻璃体内注射贝伐单抗在伊尔斯病治疗中的作用。
Int Ophthalmol. 2010 Feb;30(1):57-61. doi: 10.1007/s10792-009-9292-0. Epub 2009 Jan 23.
7
Branch retinal vein occlusion: pathogenesis, visual prognosis, and treatment modalities.视网膜分支静脉阻塞:发病机制、视觉预后及治疗方式
Curr Eye Res. 2008 Feb;33(2):111-31. doi: 10.1080/02713680701851902.
血管内皮生长因子在眼部健康与疾病中的作用。
Retina. 2005 Feb-Mar;25(2):111-8. doi: 10.1097/00006982-200502000-00001.
4
Vascular endothelial growth factor: basic science and clinical progress.血管内皮生长因子:基础科学与临床进展
Endocr Rev. 2004 Aug;25(4):581-611. doi: 10.1210/er.2003-0027.