Genersch Elke
Institute for Bee Research, Hohen Neuendorf, Germany.
Berl Munch Tierarztl Wochenschr. 2007 Jan-Feb;120(1-2):26-33.
American foulbrood, a globally spread bacterial disease of honeybee brood, is one of the most deleterious bee diseases. Its etiological agent is the gram-positive, spore-forming bacterium Paenibacillus larvae. This review will focus on recent achievements in the study of Paenibacillus larvae brought about by molecular methods introduced into the field over the last fifteen years. One topic will be the classification of the etiological agent which changed several times since the first description in 1906 and was most recently modified again. The relevance of this reclassification for laboratory diagnosis of American foulbrood will be covered. The analysis of differences in virulence of Paenibacillus larvae and the implications of these differences for transmission of the pathogen and clinical diagnosis of American foulbrood will be another thematic complex.
美洲幼虫腐臭病是一种在全球范围内传播的蜜蜂幼虫细菌性疾病，是最具危害性的蜜蜂疾病之一。其病原体是革兰氏阳性、形成芽孢的幼虫芽孢杆菌。本综述将聚焦于过去十五年间引入该领域的分子方法在幼虫芽孢杆菌研究方面取得的最新成果。一个主题将是病原体的分类，自1906年首次描述以来，该分类已多次变更，最近又再次修改。将涵盖此次重新分类对美洲幼虫腐臭病实验室诊断的相关性。幼虫芽孢杆菌毒力差异分析以及这些差异对病原体传播和美洲幼虫腐臭病临床诊断的影响将是另一个主题内容。
