• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

处于高心理社会风险的母婴二元组中的唾液皮质醇反应

Salivary cortisol response in mother-infant dyads at high psychosocial risk.

作者信息

Mörelius E, Nelson N, Gustafsson P A

机构信息

Department of Molecular and Clinical Medicine/Division of Paediatrics, Linköping University Hospital, Linköping, Sweden.

出版信息

Child Care Health Dev. 2007 Mar;33(2):128-36. doi: 10.1111/j.1365-2214.2006.00637.x.

DOI:10.1111/j.1365-2214.2006.00637.x
PMID:17291316
Abstract

OBJECTIVES

The aim of the present study was to investigate the adrenocortical response to diaper change in mother-infant dyads with psychosocial risk factors.

MATERIAL AND METHODS

Twenty-two mother-infant pairs with well-defined psychosocial problems were included. The mother-infant pairs were treated for 6 weeks in a daycare programme to improve attachment. Salivary cortisol was measured before and after a diaper change during the first and last weeks of enrollment in the programme. Mothers' sensitivity towards their infants' signals was measured using a scale from 1 (highly insensitive) to 9 (highly sensitive) according to Ainsworth.

RESULTS

Median salivary cortisol increased in 15 out of 22 infants after the first diaper change. The increase was most pronounced in the group of infants below 3 months of age (n = 15) where median salivary cortisol increased 170% after the first diaper change (P < 0.05) and decreased 19% after the last diaper change (not significant). Out of these 15 infants, 11 showed an increase in salivary cortisol in response to the first diaper change while four out of 15 did so in response to the last diaper change (P < 0.05). The salivary cortisol response did not change over time in infants aged 3 months or above. A mother's sensitivity to her child increased significantly (P < 0.001) from the first to the last week. In mothers, median salivary cortisol decreased 38% after the first diaper change (P < 0.05) and 57% after the last diaper change (P = 0.001).

DISCUSSION

A diaper change is normally not perceived as stressful. The stress response caused by a diaper change may illustrate an insufficiency in the mother-infant relationship before treatment. Professional support improved the mothers' sensitivity and stabilized the stress response to diaper change in the youngest infants.

摘要

目的

本研究旨在调查具有心理社会风险因素的母婴二元组中肾上腺皮质对换尿布的反应。

材料与方法

纳入22对存在明确心理社会问题的母婴。这些母婴对在一个日托项目中接受了6周的治疗,以改善依恋关系。在项目入学的第一周和最后一周,测量换尿布前后的唾液皮质醇水平。根据安斯沃思量表,使用从1(高度不敏感)到9(高度敏感)的量表来测量母亲对婴儿信号的敏感性。

结果

22名婴儿中有15名在第一次换尿布后唾液皮质醇中位数增加。这种增加在3个月以下的婴儿组中最为明显(n = 15),其中第一次换尿布后唾液皮质醇中位数增加了170%(P < 0.05),最后一次换尿布后下降了19%(无统计学意义)。在这15名婴儿中,11名在第一次换尿布时唾液皮质醇增加,而15名中有4名在最后一次换尿布时出现这种情况(P < 0.05)。3个月及以上婴儿的唾液皮质醇反应随时间没有变化。从第一周到最后一周,母亲对孩子的敏感性显著增加(P < 0.001)。在母亲中,第一次换尿布后唾液皮质醇中位数下降了38%(P < 0.05),最后一次换尿布后下降了57%(P = 0.001)。

讨论

换尿布通常不被认为是有压力的。换尿布引起的应激反应可能说明治疗前母婴关系存在不足。专业支持提高了母亲的敏感性,并稳定了最年幼婴儿对换尿布的应激反应。

相似文献

1
Salivary cortisol response in mother-infant dyads at high psychosocial risk.处于高心理社会风险的母婴二元组中的唾液皮质醇反应
Child Care Health Dev. 2007 Mar;33(2):128-36. doi: 10.1111/j.1365-2214.2006.00637.x.
2
Salivary cortisol and mood and pain profiles during skin-to-skin care for an unselected group of mothers and infants in neonatal intensive care.新生儿重症监护病房中一组未经挑选的母婴进行皮肤接触护理期间的唾液皮质醇、情绪及疼痛状况
Pediatrics. 2005 Nov;116(5):1105-13. doi: 10.1542/peds.2004-2440.
3
Is a nappy change stressful to neonates?给新生儿换尿布会让他们感到有压力吗?
Early Hum Dev. 2006 Oct;82(10):669-76. doi: 10.1016/j.earlhumdev.2005.12.013. Epub 2006 Feb 28.
4
The Stockholm Neonatal Family-Centered Care Study: effects on salivary cortisol in infants and their mothers.斯德哥尔摩新生儿家庭为中心的护理研究:对婴儿及其母亲唾液皮质醇的影响。
Early Hum Dev. 2012 Jul;88(7):575-81. doi: 10.1016/j.earlhumdev.2011.12.033. Epub 2012 Jan 28.
5
The association of major depression, conduct disorder, and maternal overcontrol with a failure to show a cortisol buffered response in 4-month-old infants of teenage mothers.青少年母亲的4个月大婴儿中,重度抑郁、品行障碍和母亲过度控制与未能表现出皮质醇缓冲反应之间的关联。
Biol Psychiatry. 2007 Sep 15;62(6):573-9. doi: 10.1016/j.biopsych.2006.11.009. Epub 2007 Mar 6.
6
Early dyadic patterns of mother-infant interactions and outcomes of prematurity at 18 months.母婴互动的早期二元模式与18个月时的早产结局
Pediatrics. 2006 Jul;118(1):e107-14. doi: 10.1542/peds.2005-1145.
7
Maternal soothing and infant stress responses: soothing, crying and adrenocortical activity during inoculation.母亲的安抚与婴儿的应激反应:接种疫苗期间的安抚、哭泣与肾上腺皮质活动
Infant Behav Dev. 2006 Jan;29(1):70-9. doi: 10.1016/j.infbeh.2005.08.008. Epub 2005 Oct 26.
8
Coregulation in salivary cortisol during maternal holding of premature infants.早产婴儿母亲怀抱期间唾液皮质醇的共同调节
Biol Res Nurs. 2009 Jan;10(3):226-40. doi: 10.1177/1099800408327789. Epub 2008 Nov 21.
9
Stress at three-month immunization: parents' and infants' salivary cortisol response in relation to the use of pacifier and oral glucose.三个月龄免疫接种时的应激:父母及婴儿唾液皮质醇反应与安抚奶嘴及口服葡萄糖使用的关系
Eur J Pain. 2009 Feb;13(2):202-8. doi: 10.1016/j.ejpain.2008.03.016. Epub 2008 May 16.
10
Individual differences in salivary cortisol and alpha-amylase in mothers and their infants: relation to tobacco smoke exposure.母亲及其婴儿唾液皮质醇和α-淀粉酶的个体差异:与接触烟草烟雾的关系。
Dev Psychobiol. 2007 Nov;49(7):692-701. doi: 10.1002/dev.20247.

引用本文的文献

1
Maternal cortisol concentration is associated with reduced brain activation to infant cry and more intrusive parenting behavior.产妇皮质醇浓度与婴儿哭声激活大脑减少和更具侵入性的育儿行为有关。
Psychoneuroendocrinology. 2025 Jan;171:107207. doi: 10.1016/j.psyneuen.2024.107207. Epub 2024 Oct 5.
2
Pain, Parental Involvement, and Oxytocin in the Neonatal Intensive Care Unit.新生儿重症监护病房中的疼痛、家长参与度与催产素
Front Psychol. 2019 Apr 2;10:715. doi: 10.3389/fpsyg.2019.00715. eCollection 2019.
3
Effect of skin-to-skin contact on parents' sleep quality, mood, parent-infant interaction and cortisol concentrations in neonatal care units: study protocol of a randomised controlled trial.
皮肤接触对新生儿护理单元中父母睡眠质量、情绪、父母-婴儿互动和皮质醇浓度的影响:一项随机对照试验的研究方案。
BMJ Open. 2018 Aug 1;8(7):e021606. doi: 10.1136/bmjopen-2018-021606.
4
Telomere Length in Preterm Infants: A Promising Biomarker of Early Adversity and Care in the Neonatal Intensive Care Unit?早产儿的端粒长度:新生儿重症监护病房早期逆境与护理的一个有前景的生物标志物?
Front Endocrinol (Lausanne). 2017 Oct 31;8:295. doi: 10.3389/fendo.2017.00295. eCollection 2017.
5
Biologic effects of stress and bonding in mother-infant pairs.母婴之间压力与情感联结的生物学效应。
Int J Psychiatry Med. 2016 Apr;51(3):246-57. doi: 10.1177/0091217416652382.
6
Salivary Cortisol Reactivity in Preterm Infants in Neonatal Intensive Care: An Integrative Review.新生儿重症监护病房中早产儿的唾液皮质醇反应性:一项综合综述。
Int J Environ Res Public Health. 2016 Mar 18;13(3):337. doi: 10.3390/ijerph13030337.
7
Closeness and separation in neonatal intensive care.新生儿重症监护中的亲近与分离。
Acta Paediatr. 2012 Oct;101(10):1032-7. doi: 10.1111/j.1651-2227.2012.02787.x. Epub 2012 Aug 2.
8
Family nurture intervention (FNI): methods and treatment protocol of a randomized controlled trial in the NICU.家庭养育干预(FNI):NICU 中一项随机对照试验的方法和治疗方案。
BMC Pediatr. 2012 Feb 7;12:14. doi: 10.1186/1471-2431-12-14.
9
Pharmacotherapeutic intervention in impulsive preschool children: The need for a comprehensive therapeutic approach.药物治疗干预冲动型学龄前儿童:需要综合治疗方法。
Child Adolesc Psychiatry Ment Health. 2011 Apr 13;5(1):11. doi: 10.1186/1753-2000-5-11.
10
Stress responses of neonates related to maternal characteristics.新生儿与产妇特征相关的应激反应。
Yonsei Med J. 2011 Jan;52(1):98-103. doi: 10.3349/ymj.2011.52.1.98.