Department of Nursing, Honam University, Gwangju, Korea.
Yonsei Med J. 2011 Jan;52(1):98-103. doi: 10.3349/ymj.2011.52.1.98.
To investigate the pre- and post-heelstick stress response patterns of infants and to identify related maternal factors.
Fifty-two mothers and their 57 infants were studied. Stress response patterns in neonates were collected by measurements of pulse rate, oxygen saturation, and salivary cortisol. Maternal demographic factors and awakening saliva were collected.
Median level of pulse rate of infant increased from 132.1 to 140.4 beats per minute and salivary cortisol was elevated from 0.41 μg/dL to 0.70 μg/dL during the periods of discomfort, while oxygen saturation decreased from 97% to 95%. Infant's pulse rate change was negatively correlated with gestational age (GA) (r = - 0.37, p < 0.05), whereas the change of infants' salivary cortisol was correlated positively with maternal age (r = 0.29, p < 0.05). GA was the only independently significant predictor of pulse rate responses (R(2) = 0.15, p < 0.05). Influence of maternal age on infants' salivary cortisol changes (R(2) = 0.09, p < 0.05) was observed in a stepwise multiple regression.
These findings suggest that maternal age and gestational period can be influential factors for stress responses in infants. Therefore, it would be important to consider the demographic characteristics of mother-infant pairs to evaluate these influential factors.
研究足跟采血前和足跟采血后的婴儿应激反应模式，并确定相关的产妇因素。
研究了 52 位母亲及其 57 位婴儿。通过测量脉搏率、血氧饱和度和唾液皮质醇来收集新生儿的应激反应模式。收集产妇的人口统计学因素和觉醒唾液。
婴儿的脉搏率中位数从 132.1 次/分钟增加到 140.4 次/分钟，而唾液皮质醇从 0.41μg/dL 升高到 0.70μg/dL，在此期间，血氧饱和度从 97%下降到 95%。婴儿脉搏率的变化与胎龄（GA）呈负相关（r=-0.37，p<0.05），而婴儿唾液皮质醇的变化与产妇年龄呈正相关（r=0.29，p<0.05）。GA 是脉搏率反应的唯一独立显著预测因子（R²=0.15，p<0.05）。在逐步多元回归中观察到产妇年龄对婴儿唾液皮质醇变化的影响（R²=0.09，p<0.05）。
这些发现表明，产妇年龄和胎龄是婴儿应激反应的影响因素。因此，考虑母婴对的人口统计学特征来评估这些影响因素非常重要。
