患有精神分裂症及共病的暴力者：一项功能磁共振成像研究。
Violent persons with schizophrenia and comorbid disorders: a functional magnetic resonance imaging study.
作者信息
Joyal C C, Putkonen A, Mancini-Marïe A, Hodgins S, Kononen M, Boulay L, Pihlajamaki M, Soininen H, Stip E, Tiihonen J, Aronen H J
机构信息
Niuvanniemi Hospital, Kuopio, Finland.
出版信息
Schizophr Res. 2007 Mar;91(1-3):97-102. doi: 10.1016/j.schres.2006.12.014. Epub 2007 Feb 7.
The main goal of this functional Magnetic Resonance Imaging (fMRI) study was to verify the hypothesis that seriously violent persons with Sz and the co-morbid diagnoses of an Antisocial Personality Disorder (APD) and a Substance Use Disorder (Sz+APD+SUD) would present a different pattern of prefrontal functioning than seriously violent persons with Sz only. In support with the main hypothesis, frontal basal cortices were significantly less activated in persons with Sz+APD+SUD during the execution of a go/no-go task than in persons with Sz only and non-violent persons without a mental illness. In contrast, significantly higher activations in frontal motor, premotor and anterior cingulate regions were observed in the Sz+APD+SUD group than in the Sz-only group.
这项功能磁共振成像（fMRI）研究的主要目标是验证以下假设：患有精神分裂症（Sz）且合并反社会人格障碍（APD）和物质使用障碍（Sz+APD+SUD）的严重暴力者，其前额叶功能模式与仅患有精神分裂症的严重暴力者不同。支持这一主要假设的是，在执行停止信号任务时，患有Sz+APD+SUD的人额叶基底皮质的激活程度明显低于仅患有精神分裂症的人和没有精神疾病的非暴力者。相比之下，Sz+APD+SUD组在前额叶运动区、运动前区和前扣带回区域的激活程度明显高于仅患有精神分裂症的组。
Zotero 插件