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非反刍动物的淀粉消化与吸收

Starch digestion and absorption in nonruminants.

作者信息

Gray G M

机构信息

Gastroenterology Division, Stanford University School of Medicine, CA 94305.

出版信息

J Nutr. 1992 Jan;122(1):172-7. doi: 10.1093/jn/122.1.172.

Abstract

Starch digestion and absorption is augmented appreciably by physical processing of grain or legume and by heating to 100 degrees C for several minutes before its ingestion. Starch, a polysaccharide composed of alpha 1,4-linked glucose units (amylose) and alpha 1,4-1,6-linked branched structure (amylopectin), is cleaved in the duodenal cavity by secreted pancreatic alpha-amylase to a disaccharide (maltose), trisaccharide (maltotriose), and branched alpha-dextrins. These final oligosaccharides are hydrolyzed efficiently by complimentary action of three integral brush border enzymes at the intestinal surface: glucoamylase (maltase-glucoamylase, amyloglucosidase), sucrase (maltase-sucrase) and alpha-dextrinase (isomaltase). The final monosaccharide glucose product is then cotransported into the enterocyte along with Na+ by a specific brush border 75-kDa transport protein in the rate-limiting step for overall starch assimilation. By virtue of this sequential luminal and membrane digestion followed by glucose transport, starch is assimilated in a very efficient manner in nonruminants.

摘要

谷物或豆类经过物理加工以及在摄入前加热至100摄氏度几分钟,可显著增强淀粉的消化和吸收。淀粉是一种由α-1,4-连接的葡萄糖单元(直链淀粉)和α-1,4-1,6-连接的分支结构(支链淀粉)组成的多糖,在十二指肠腔内被分泌的胰腺α-淀粉酶分解为二糖(麦芽糖)、三糖(麦芽三糖)和分支α-糊精。这些最终的寡糖通过肠道表面三种完整的刷状缘酶的协同作用被有效水解:葡糖淀粉酶(麦芽糖酶-葡糖淀粉酶、淀粉葡糖苷酶)、蔗糖酶(麦芽糖酶-蔗糖酶)和α-糊精酶(异麦芽糖酶)。最终的单糖葡萄糖产物然后通过一种特定的75 kDa刷状缘转运蛋白与Na+一起共转运进入肠上皮细胞,这是整个淀粉同化的限速步骤。由于这种先在管腔和膜上进行的连续消化以及随后的葡萄糖转运,淀粉在非反刍动物中以非常有效的方式被同化。

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