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体外成熟周期中源自体外成熟卵母细胞的人囊胚移植后的妊娠与分娩

Pregnancies and deliveries after transfer of human blastocysts derived from in vitro matured oocytes in in vitro maturation cycles.

作者信息

Son Weon-Young, Lee Seok-Yoon, Yoon San-Huyn, Lim Jin-Ho

机构信息

McGill Reproductive Center, Department of Obstetrics and Gynecology, Royal Victoria Hospital, McGill University, Montreal, Canada.

出版信息

Fertil Steril. 2007 Jun;87(6):1491-3. doi: 10.1016/j.fertnstert.2006.11.027. Epub 2007 Feb 12.

Abstract

A total of 82 patients underwent 106 cycles in which immature oocytes were recovered after hCG priming and transferred at blastocyst-stage. After transfer, the implantation rate was 26.8%, and the clinical pregnancy rate was 51.9%. We found that the oocytes retrieved after hCG priming in women with high risk of ovarian hyperstimulation syndrome in the in vitro maturation program can develop to blastocyst, and pregnancies can be established by transfer of the blastocysts.

摘要

共有82例患者接受了106个周期的治疗,这些周期中在注射人绒毛膜促性腺激素(hCG)预处理后回收未成熟卵母细胞,并在囊胚期进行移植。移植后,着床率为26.8%,临床妊娠率为51.9%。我们发现,在体外成熟程序中,有卵巢过度刺激综合征高风险的女性在hCG预处理后回收的卵母细胞能够发育至囊胚,通过移植这些囊胚可以实现妊娠。

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