Aleksenko Larysa, Gyasi Rk
Department of Pathology, University of Ghana Medical School, P O Box 4236, Accra.
Ghana Med J. 2005 Sep;39(3):108-11.
SummaryWe report a case of perinatal death from hypoglycaemia in an infant of a mother who had fasting hyperglycaemia diagnosed at 31 weeks of gestation and managed with diet alone. Blood glucose values were not conclusive of gestational impaired glucose tolerance by WHO and American Diabetes Association standards, yet autopsy histological findings in the pancreas were similar to that described in neonates of a diabetic mother. We therefore emphasize that all pregnant women with inconclusive glucose values for diagnosis of full blown gestational diabetes mellitus should be fully investigated and closely monitored during antenatal care. The infants of such mothers may be at a higher risk of hypoglycemia in the immediate post natal period and would require similar monitoring and aggressive management.
摘要
我们报告了一例围产期死亡病例,患儿母亲在妊娠31周时被诊断为空腹血糖升高,仅通过饮食管理。根据世界卫生组织和美国糖尿病协会的标准,血糖值不能确诊为妊娠期糖耐量受损,但胰腺的尸检组织学结果与糖尿病母亲的新生儿相似。因此,我们强调,所有血糖值不能确诊为显性妊娠期糖尿病的孕妇,在产前护理期间都应进行全面检查并密切监测。这类母亲的婴儿在出生后即刻发生低血糖的风险可能更高,需要进行类似的监测和积极管理。