Kitcher Ed, Yarney J, Gyasi Rk, Cheyuo C
Department of Surgery University of Ghana Medical School, P O Box 4236 Accra.
Ghana Med J. 2006 Jun;40(2):45-9. doi: 10.4314/gmj.v40i2.36016.
Laryngeal cancer is the commonest Head and Neck cancer seen at the Ear Nose and Throat (ENT) Unit Korle-Bu Teaching Hospital. The aim of this study was to determine the number of cases of laryngeal cancer seen at the Korle Bu Teaching Hospital, establish epidemiological parameters of the disease and to outline preventive measures.
One hundred and fifteen (115) patients who were managed for laryngeal cancer from 1(st) January 1998 to 31(st) December 2003 were studied retrospectively with respect to age, sex, duration of symptoms at presentation, risk factors, symptoms complex, histopathology, stage of tumor, details of treatment offered and follow up.
The age range was 17-85 years with a mean of 55.5 years (SD10.7). Majority of the patients (90.4%) were above 40 years. The commonest symptom at presentation was dysphonia. A significant proportion of cases (37.3%) presented with locally advanced disease. The commonest histological type of laryngeal tumour seen was squamous cell carcinoma. The treatment offered consisted of radiotherapy for 83 (79.8%) patients and total laryngectomy with neck dissection when necessary for 17 (16.3%) patients who also had postoperative radiotherapy. Only 58 (69.9%) patients completed radiotherapy treatment and in all 32 (24.3 %) patients did not report for any treatment. Majority of patients failed to report for post treatment follow up.
We conclude that significant number of patients with laryngeal cancer presented with locally advanced disease and dysphonia was the commonest symptom.
摘要 引言:喉癌是在科勒-布教学医院耳鼻喉科所见的最常见的头颈癌。本研究的目的是确定在科勒-布教学医院所见的喉癌病例数,确立该疾病的流行病学参数,并概述预防措施。
对1998年1月1日至2003年12月31日期间接受喉癌治疗的115例患者进行回顾性研究,内容包括年龄、性别、就诊时症状持续时间、危险因素、症状复合体、组织病理学、肿瘤分期、所提供的治疗细节及随访情况。
年龄范围为17至85岁,平均年龄55.5岁(标准差10.7)。大多数患者(90.4%)年龄在40岁以上。就诊时最常见的症状是声音嘶哑。相当比例的病例(37.3%)表现为局部晚期疾病。所见的最常见的喉肿瘤组织学类型是鳞状细胞癌。所提供的治疗包括83例(79.8%)患者接受放疗,17例(16.3%)患者必要时行全喉切除术及颈部清扫术,这些患者术后也接受放疗。只有58例(69.9%)患者完成了放疗疗程,共有32例(24.3%)患者未接受任何治疗。大多数患者未进行治疗后随访。
我们得出结论,相当数量的喉癌患者表现为局部晚期疾病,声音嘶哑是最常见的症状。