Pombo Romero Julio, Portela Romero Manuel, Vizoso Hermida José Ramón, Tasende Souto Margarita
Dirección General de Farmacia y Productos Sanitarios, Consellería de Sanidade de Galicia, Santiago de Compostela, A Coruña, España.
Gac Sanit. 2007 Jan-Feb;21(1):18-23; discussion 23-4. doi: 10.1157/13099115.
To quantify, from an economic perspective, the results of the Pilot Program of Dispensation of Medicines in Unitary Dose in Galicia, Spain.
Retrospective study from 35,923 antibiotic prescriptions in customized doses corresponding to 5 active principles (amoxicillin, amoxicilin/clavulanic, claritromicin, cefuroxima axetil and ciprofloxacin). The program, which worked during 12 months, included 292 physicians from 46 units of primary care of the Galician Health Service and 167 offices of pharmacy.
60.57% of the prescribed treatments did not adjust exactly to the conventional presentations existing in the market. Savings in units of antibiotic of the dispensation in customized doses compared with the conventional one has been of 14.32%. Registered economic saving has been of 29.94%. The inclusion of 2 new presentations in amoxiciline and amoxiciline/clavulanic (of 15 and 21 tablets) and of one in the other 3 (cefuroxime and ciprofloxacin of 14 tablets and clarithromycin of 16) would avoid 86.5% of the leftover units without having to implement individualized dispensation.
An important antibiotic stock is being generated in home medicine cabinets as a result of the leftovers of prescribed treatments that in the case of Galicia are equivalent to more than 1,800,000 doses of antibiotic in 2004. This problem could be reduced with the dispensation in customized dose and partially with new presentations.
从经济角度量化西班牙加利西亚地区单一剂量药品配给试点项目的成果。
对35923份对应5种活性成分（阿莫西林、阿莫西林/克拉维酸、克拉霉素、头孢呋辛酯和环丙沙星）的定制剂量抗生素处方进行回顾性研究。该项目实施了12个月，参与的有来自加利西亚卫生服务机构46个初级保健单位的292名医生以及167家药房。
60.57%的处方治疗方案与市场上现有的常规剂型不完全匹配。与常规剂型相比，定制剂量配给的抗生素单位节省量为14.32%。已记录的经济节省量为29.94%。在阿莫西林和阿莫西林/克拉维酸中加入2种新剂型（分别为15片和21片），在其他3种药物（头孢呋辛14片、环丙沙星14片和克拉霉素16片）中加入1种新剂型，将避免86.5%的剩余单位，而无需实施个体化配给。
由于处方治疗的剩余药物，家庭药柜中产生了大量抗生素库存，在加利西亚地区，2004年这相当于超过180万剂抗生素。定制剂量配给以及部分新剂型的使用可以减少这个问题。
