Kiliç Süleyman, Aksoy Yüksel, Sincer Isa, Oğuz Fatih, Erdil Nevzat, Yetkin Ertan
Department of Urology, Inonu University School of Medicine, Malatya, Turkey.
Fertil Steril. 2007 Aug;88(2):369-73. doi: 10.1016/j.fertnstert.2006.11.119. Epub 2007 Feb 20.
To evaluate cardiovascular risk factors and demographic parameters in patients with varicocele.
Although some pathophysiologic hypotheses have been suggested to explain the etiology of varicocele, the exact mechanism underlying varicocele is not yet known. The coexistence of arterial and venous system pathologic conditions has been reported recently, including varicosities of the coronary venous system and leg veins. Cardiovascular risk factors have not been evaluated previously in patients with varicocele. In addition to the presence of cardiovascular risk factors and demographic parameters, we assessed the prevalence of peripheral varicose veins in patients with and without varicocele.
PATIENT(S): Study groups consisted of 52 patients with varicocele and 100 patients without varicocele younger than 50 years old.
RESULT(S): There were no statistically significant differences between the two groups with respect to presence of hypertension, diabetes mellitus, hyperlipidemia, family history of coronary artery disease, body mass index, age, and height. The weight and presence of peripheral varicose veins in the patients with varicocele were significantly higher than in those without varicocele. It was found that presence of peripheral varicose veins was independently and positively associated with varicocele.
CONCLUSION(S): We have demonstrated that varicocele is not associated with cardiovascular risk factors or demographic parameters. However, the presence of peripheral varicose veins is positively associated with varicocele, suggesting a possible common pathologic step.
评估精索静脉曲张患者的心血管危险因素和人口统计学参数。
尽管已经提出了一些病理生理假说来解释精索静脉曲张的病因，但精索静脉曲张的确切潜在机制尚不清楚。最近有报道称动脉和静脉系统病理状况并存，包括冠状静脉系统和腿部静脉的静脉曲张。此前尚未对精索静脉曲张患者的心血管危险因素进行评估。除了心血管危险因素和人口统计学参数外，我们还评估了有和没有精索静脉曲张患者外周静脉曲张的患病率。
研究组由52例年龄小于50岁的精索静脉曲张患者和100例无精索静脉曲张患者组成。
两组在高血压、糖尿病、高脂血症、冠状动脉疾病家族史、体重指数、年龄和身高方面无统计学显著差异。精索静脉曲张患者的体重和外周静脉曲张的患病率显著高于无精索静脉曲张的患者。发现外周静脉曲张的存在与精索静脉曲张独立且呈正相关。
我们已经证明精索静脉曲张与心血管危险因素或人口统计学参数无关。然而，外周静脉曲张的存在与精索静脉曲张呈正相关，提示可能存在共同的病理步骤。
