精索静脉曲张矫正术能否使术前升高的平均血小板体积水平恢复正常？
Does varicocele correction lead to normalization of preoperatively elevated mean platelet volume levels?
作者信息
Coban Soner, Keles Ibrahim, Biyik İsmail, Guzelsoy Muhammet, Turkoglu Ali Rıza, Ocak Nihal
机构信息
Department of Urology, Şevket Yılmaz Training and Research Hospital, Bursa, Turkey;
Department of Urology, School of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey;
出版信息
Can Urol Assoc J. 2015 Jan-Feb;9(1-2):E5-9. doi: 10.5489/cuaj.2113.
INTRODUCTION
There are several studies on the relationship between increased mean platelet volume (MPV) and varicocele. We investigated the relationship between preoperative and 6-month postoperative MPV values in patients whose varicocele was corrected with surgery.
METHODS
A total of 282 patients underwent surgery at our urology clinic between December 2011 and December 2013 for primary varicocele. We retrospectively examined the records of 61 patients who came to the 6-month postoperative follow-up. The preoperative varicocele diagnosis was made with physical examination findings and supported with colour Doppler ultrasonography.
RESULTS
The varicocele was grade I in 12 patients, grade II in 34 patients and grade III in 11 patients. When the preoperative and 6-month postoperative haemoglobin (Hb), MPV, mean corpuscular volume, platelet, and platelet distribution width (PDW) values were compared, there was a significant decrease in MPV (p = 0.019), and a significant increase in Hb (p < 0.001). A noticeable increase was also present in PDW, but it was not statistically significant (p = 0.058).
CONCLUSION
We found that MPV increased in patients with varicocele and tended to decrease again after the varicocele was surgically corrected. However, we feel larger prospective series are needed.
引言
关于平均血小板体积（MPV）增加与精索静脉曲张之间的关系已有多项研究。我们调查了精索静脉曲张手术矫正患者术前和术后6个月MPV值之间的关系。
方法
2011年12月至2013年12月期间，共有282例患者在我们的泌尿外科诊所接受了原发性精索静脉曲张手术。我们回顾性检查了61例术后6个月随访患者的记录。术前通过体格检查结果诊断精索静脉曲张，并辅以彩色多普勒超声检查。
结果
精索静脉曲张I级12例，II级34例，III级11例。比较术前和术后6个月的血红蛋白（Hb）、MPV、平均红细胞体积、血小板和血小板分布宽度（PDW）值，MPV显著降低（p = 0.019），Hb显著升高（p < 0.001）。PDW也有明显升高，但无统计学意义（p = 0.058）。
结论
我们发现精索静脉曲张患者的MPV升高，精索静脉曲张手术矫正后MPV又趋于下降。然而，我们认为需要更大规模的前瞻性研究系列。
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