Deltour Laetitia, Barathon Marion, Quaglino Véronique, Vernier Marie-Pierre, Despretz Pascal, Boucart Muriel, Berquin Patrick
CHU Amiens, Hôpital Nord, Dept Pédiatrie, Neurologie Pédiatrique & Lab, Neurosciences Fonctionnelles & Pathologies (CNRS UMR 8160), Amiens, France.
Epileptic Disord. 2007 Mar;9(1):32-8. doi: 10.1684/epd.2007.0066. Epub 2007 Feb 15.
Children with epilepsy often have attention deficits, even when epilepsy is idiopathic and benign. The mechanisms underlying attention deficits are still unknown and appear to be different between focal and generalized epilepsy. In this study, an attentional capture paradigm was used to study and compare one aspect of attentional control, the resistance to interference from distractors, in 18 children with benign epilepsy with centrotemporal spikes (BECTS), 18 children with idiopathic generalized epilepsy and 18 controls aged 7-12 years. The results showed longer response times (RT) and more omissions in the two groups with epilepsy compared to controls. Attentional capture with longer response times in trials with a moving distractor compared to baseline condition with stationary distractors was found in both controls and children with epilepsy. The magnitude of interference from moving distractors was greater in the BECTS group than in the idiopathic generalized epilepsy group and in the controls group. These results suggest an impact of epilepsy on resistance to interference from distractors in children with BECTS.
患有癫痫的儿童经常存在注意力缺陷，即使癫痫是特发性和良性的。注意力缺陷背后的机制仍然未知，并且在局灶性癫痫和全身性癫痫之间似乎有所不同。在本研究中，采用注意力捕获范式来研究和比较18名患有中央颞区棘波的良性癫痫（BECTS）儿童、18名特发性全身性癫痫儿童和18名7至12岁对照儿童注意力控制的一个方面，即对干扰物干扰的抵抗力。结果显示，与对照组相比，两组癫痫患儿的反应时间（RT）更长，遗漏更多。在对照组和癫痫患儿中，与静止干扰物的基线条件相比，在有移动干扰物的试验中注意力捕获的反应时间更长。BECTS组中移动干扰物的干扰程度大于特发性全身性癫痫组和对照组。这些结果表明癫痫对BECTS儿童抵抗干扰物干扰的能力有影响。
