Lim K O, Zipursky R B, Watts M C, Pfefferbaum A
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, California.
J Gerontol. 1992 Jan;47(1):B26-30. doi: 10.1093/geronj/47.1.b26.
Using in vivo magnetic resonance (MR) images, the percentages of gray matter, white matter, and cerebrospinal fluid (CSF) in the brains of 8 young and 6 elderly normal male community volunteers were quantified. Compared with the young men, the elderly men had a significantly lower percentage of gray matter (p less than .01) and higher percentage of CSF (p less than .01). The percentage of white matter was not significantly different between the two groups. This finding suggests that the age-related decrease in brain tissue is chiefly due to loss of gray matter.
利用体内磁共振（MR）图像，对8名年轻和6名老年正常男性社区志愿者大脑中的灰质、白质和脑脊液（CSF）百分比进行了量化。与年轻男性相比，老年男性的灰质百分比显著降低（p < 0.01），脑脊液百分比更高（p < 0.01）。两组之间白质的百分比没有显著差异。这一发现表明，与年龄相关的脑组织减少主要是由于灰质的丧失。
