Khunti Kamlesh, Stone Margaret, Paul Sanjoy, Baines Jan, Gisborne Louise, Farooqi Azhar, Luan Xiujie, Squire Iain
Department of Health Sciences, University of Leicester, UK.
Heart. 2007 Nov;93(11):1398-405. doi: 10.1136/hrt.2006.106955. Epub 2007 Feb 19.
To evaluate the effect of a disease management programme for patients with coronary heart disease (CHD) and chronic heart failure (CHF) in primary care.
A cluster randomised controlled trial of 1316 patients with CHD and CHF from 20 primary care practices in the UK was carried out. Care in the intervention practices was delivered by specialist nurses trained in the management of patients with CHD and CHF. Usual care was delivered by the primary healthcare team in the control practices.
At follow up, significantly more patients with a history of myocardial infarction in the intervention group were prescribed a beta-blocker compared to the control group (adjusted OR 1.43, 95% CI 1.19 to 1.99). Significantly more patients with CHD in the intervention group had adequate management of their blood pressure (<140/85 mm Hg) (OR 1.61, 95% CI 1.22 to 2.13) and their cholesterol (<5 mmol/l) (OR 1.58, 95% CI 1.05 to 2.37) compared to those in the control group. Significantly more patients with an unconfirmed diagnosis of CHF had a diagnosis of left ventricular systolic dysfunction confirmed (OR 4.69, 95% CI 1.88 to 11.66) or excluded (OR 3.80, 95% CI 1.50 to 9.64) in the intervention group compared to the control group. There were significant improvements in some quality-of-life measures in patients with CHD in the intervention group.
Disease management programmes can lead to improvements in the care of patients with CHD and presumed CHF in primary care.
评估一项针对基层医疗中冠心病(CHD)和慢性心力衰竭(CHF)患者的疾病管理项目的效果。
对来自英国20家基层医疗诊所的1316例CHD和CHF患者进行了一项整群随机对照试验。干预诊所的护理由接受过CHD和CHF患者管理培训的专科护士提供。常规护理由对照组诊所的基层医疗团队提供。
随访时,与对照组相比,干预组中既往有心肌梗死病史的患者使用β受体阻滞剂的比例显著更高(校正比值比1.43,95%可信区间1.19至1.99)。与对照组相比,干预组中更多的CHD患者血压得到充分控制(<140/85 mmHg)(比值比1.61,95%可信区间1.22至2.13),胆固醇得到充分控制(<5 mmol/L)(比值比1.58,95%可信区间1.05至2.37)。与对照组相比,干预组中更多未经确诊的CHF患者确诊为左心室收缩功能障碍(比值比4.69,95%可信区间1.88至11.66)或排除该诊断(比值比3.80,95%可信区间1.50至9.64)。干预组中CHD患者的一些生活质量指标有显著改善。
疾病管理项目可改善基层医疗中CHD和疑似CHF患者的护理。