Modlin Irvin M, Shapiro Michael D, Kidd Mark, Eick Geeta
Gastric Pathobiology Research Group, Department of Surgery, Yale University School of Medicine, New Haven, CT 06520-8062, USA.
Arch Surg. 2007 Feb;142(2):187-97. doi: 10.1001/archsurg.142.2.187.
Siegfried Oberndorfer was born in Munich, Germany, in 1876, studied medicine at the University of Munich, and became the youngest Jewish physician to be appointed to its faculty (1907). His unique observations regarding multiple small-intestinal tumors were presented at the German Pathological Society convention (Dresden, Germany, September 1907), where he coined the term karzinoide and published it in December of the same year. Twenty-two years later (in 1929), he amended this report and suggested that carcinoid tumors might also exhibit malignant features and metastasize. The rise of Nazism led to the termination of his position in 1933, and he "emigrated" to Turkey to serve as the chair of anatomical pathology at the University of Istanbul, Istanbul, Turkey, where he remained until his death in 1944. This exploration of his life and times seeks to give Oberndorfer his well-deserved place in the pantheon of pathology and memorialize his unique observations that led to the discovery of the carcinoid tumor.
西格弗里德·奥本多夫于1876年出生在德国慕尼黑，在慕尼黑大学学习医学，并成为该校教员中最年轻的犹太医生（1907年）。他关于多种小肠肿瘤的独特观察结果在德国病理学会大会（1907年9月，德国德累斯顿）上发表，在会上他创造了“karzinoide”一词，并于同年12月发表。22年后（1929年），他修订了这份报告，并提出类癌肿瘤也可能表现出恶性特征并发生转移。纳粹主义的兴起导致他在1933年失去职位，他“移民”到土耳其，担任土耳其伊斯坦布尔大学解剖病理学系主任，一直任职到1944年去世。对他的生平与时代的探究旨在给予奥本多夫在病理学万神殿中应有的地位，并纪念他那些促成类癌肿瘤发现的独特观察结果。
