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远程钴治疗机用于立体定向放射治疗的适配

Adaptation of telecobalt unit for stereotactic irradiation.

作者信息

Singh I Rabi Raja, Ravindran B Paul, Ayyangar K M

机构信息

Department of Radiotherapy, Christian Medical College, Vellore, 632004, India.

出版信息

Med Dosim. 2007 Spring;32(1):52-8. doi: 10.1016/j.meddos.2006.11.001.

Abstract

We investigated the feasibility of using an isocentric telecobalt unit for advanced treatment techniques, such as stereotactic radiotherapy. To adapt the telecobalt unit (Th780 C) for stereotactic irradiation, collimator inserts of various sizes, collimator mount, and a couch mount suitable for the telecobalt unit were developed, and the characteristics of the narrow beams of Cobalt-60 (60Co) were studied. Comparative study was carried out between the stereotactic radiotherapy plans of 6 MV and 60Co beams using a 3-dimensional (3D) treatment planning system. The beam penumbra of 60Co beams was found to be larger than those of 6 MV beams. The dose-volume histograms (DVH) obtained from the 60Co beam plan were comparable to those obtained from the 6 MV plan. The DVH of nontarget tissue obtained from the plans of the 2 beams were found to be in good agreement to each other. The difference in equivalent fall-off distance (EFOD) for all 3 cases was found insignificant; hence, it can be concluded that the fall-off dose in the dose distribution of the 60Co stereotactic plan is as good as that of the 6 MV stereotactic plan. In all 3 cases for which the treatment plans were compared between 60Co and 6 MV beams, it was observed that the fall-off doses outside the target were similar; therefore, considering 60Co with 5-mm margin is a cost effective alternative for the linac-based stereotactic radiotherapy.

摘要

我们研究了使用等中心远距钴治疗机用于立体定向放射治疗等先进治疗技术的可行性。为使远距钴治疗机(Th780 C)适用于立体定向照射,开发了各种尺寸的准直器插件、准直器支架以及适合该远距钴治疗机的治疗床支架,并研究了钴-60(60Co)窄束的特性。使用三维(3D)治疗计划系统对6兆伏(MV)和60Co射线束的立体定向放射治疗计划进行了对比研究。发现60Co射线束的半值层比6 MV射线束的大。从60Co射线束计划获得的剂量体积直方图(DVH)与从6 MV计划获得的相当。从这两种射线束计划获得的非靶组织的DVH彼此吻合良好。发现所有3种情况的等效衰减距离(EFOD)差异不显著;因此,可以得出结论,60Co立体定向计划剂量分布中的衰减剂量与6 MV立体定向计划的一样好。在对60Co和6 MV射线束的治疗计划进行比较的所有3种情况中,观察到靶区外的衰减剂量相似;因此,对于基于直线加速器的立体定向放射治疗,考虑使用有5毫米边缘的60Co是一种具有成本效益的替代方案。

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