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外部因素加速了重复基因之间的表达差异。

External factors accelerate expression divergence between duplicate genes.

作者信息

Ha Misook, Li Wen-Hsiung, Chen Z Jeffrey

机构信息

Section of Molecular Cell and Developmental Biology and Institute for Cellular and Molecular Biology, One University Station, A-4800, University of Texas, Austin, TX 78712-0159, USA.

出版信息

Trends Genet. 2007 Apr;23(4):162-6. doi: 10.1016/j.tig.2007.02.005. Epub 2007 Feb 22.

Abstract

We examined the evolution of expression of duplicate genes in Arabidopsis thaliana, by analyzing 512 data sets of gene expression microarrays and 2022 recent duplicate gene pairs. Expression divergence between gene duplicates is significantly greater in response to environmental stress than to developmental processes. A slow rate of expression divergence during development might offer dosage-dependent selective advantage, whereas rapid expression divergence in response to external changes might accelerate adaptation.

摘要

我们通过分析512个基因表达微阵列数据集和2022对近期重复基因对,研究了拟南芥中重复基因的表达演变。基因重复体之间的表达差异在对环境胁迫的响应中显著大于对发育过程的响应。发育过程中表达差异的缓慢速率可能提供剂量依赖性的选择优势,而对外部变化的快速表达差异可能加速适应性。

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