Brenes Gretchen A, Kritchevsky Stephen B, Mehta Kala M, Yaffe Kristine, Simonsick Eleanor M, Ayonayon Hilsa N, Rosano Caterina, Rubin Susan M, Satterfield Suzanne, Penninx Brenda W J H
Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
Am J Geriatr Psychiatry. 2007 Mar;15(3):262-5. doi: 10.1097/JGP.0b013e31802e21f0.
The purpose of this study is to determine if anxiety is associated with mortality and if race moderates and depression mediates this relationship.
Participants are 3,015 adults aged 70-79 years.
Anxiety symptoms were significant predictors of all-cause, cardiovascular, and noncardiovascular mortality among blacks but not whites. Depression was not related to mortality.
Although the mechanisms that underlie the relationship between anxiety and mortality are unknown, routine assessment of anxiety symptoms in clinical practice, particularly in black older adults, seems prudent.
本研究旨在确定焦虑是否与死亡率相关，以及种族是否起调节作用、抑郁是否起中介作用。
研究对象为3015名70 - 79岁的成年人。
焦虑症状是黑人全因死亡、心血管疾病死亡和非心血管疾病死亡的显著预测因素，而在白人中并非如此。抑郁与死亡率无关。
尽管焦虑与死亡率之间关系的潜在机制尚不清楚，但在临床实践中对焦虑症状进行常规评估似乎是谨慎之举，尤其是在老年黑人中。
