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伴有或不伴有胰管支架置入的胰石清除术后的结局

Outcomes after clearance of pancreatic stones with or without pancreatic stenting.

作者信息

Sasahira Naoki, Tada Minoru, Isayama Hiroyuki, Hirano Kenji, Nakai Yousuke, Yamamoto Natsuyo, Tsujino Takeshi, Toda Nobuo, Komatsu Yutaka, Yoshida Haruhiko, Kawabe Takao, Omata Masao

机构信息

Department of Gastroenterology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

出版信息

J Gastroenterol. 2007 Jan;42(1):63-9. doi: 10.1007/s00535-006-1972-1. Epub 2007 Feb 16.

Abstract

BACKGROUND

Extracorporeal shockwave lithotripsy (ESWL) and endoscopic lithotripsy are useful for the fragmentation and extraction of pancreatic stones. However, pancreatic stones often recur, for which an adequate strategy is needed. Treatment for stricture of the main pancreatic duct (MPD) with a pancreatic stent after clearance of pancreatic stones may reduce the recurrence of pancreatic symptoms and stones.

METHODS

Forty patients with chronic pancreatitis with MPD stones were treated with ESWL in combination with endoscopic stone extraction. After clearance of the stones, a pancreatic stent was inserted when a stricture of MPD was observed on pancreatography. The stent was exchanged every 3 months and removed after a total of 1 year. We examined episodes of recurrent pain and pancreatitis in patients with and without stenting, as well as the MPD diameter, during follow-up.

RESULTS

MPD stricture was seen in 27 patients, and a stent was successfully inserted in 24 of them. Pancreatic symptoms recurred in five patients (21%) in the stenting group and in three patients (23%) in the control group during a mean follow-up period of 1.5 and 1.2 years, respectively. The diameter of the MPD, before, just after, and 1 year after treatment, was 7.6, 5.4, and 5.8 mm, respectively. It was significantly decreased after 1 year of follow-up, as well as just after stent removal, compared with before treatment (P < 0.05).

CONCLUSIONS

Additional stenting for MPD after extraction of pancreatic stones may reduce the risk of recurrence of pancreatic symptoms.

摘要

背景

体外冲击波碎石术(ESWL)和内镜下碎石术对于胰腺结石的破碎和取出很有用。然而,胰腺结石常复发,对此需要一种合适的策略。胰腺结石清除后放置胰腺支架治疗主胰管(MPD)狭窄可能会降低胰腺症状和结石的复发率。

方法

40例患有MPD结石的慢性胰腺炎患者接受了ESWL联合内镜下结石取出术治疗。结石清除后,若在胰管造影时观察到MPD狭窄,则插入胰腺支架。支架每3个月更换一次,共放置1年后取出。我们在随访期间检查了有或无支架置入患者的复发性疼痛和胰腺炎发作情况,以及MPD直径。

结果

27例患者出现MPD狭窄,其中24例成功置入支架。在平均1.5年和1.2年的随访期内,支架置入组有5例患者(21%)出现胰腺症状复发,对照组有3例患者(23%)出现复发。治疗前、治疗后即刻和治疗后1年MPD的直径分别为7.6 mm、5.4 mm和5.8 mm。与治疗前相比,随访1年后以及支架取出后即刻MPD直径均显著减小(P < 0.05)。

结论

胰腺结石取出后对MPD进行额外的支架置入可能会降低胰腺症状复发的风险。

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