Anderson P G, Bajaj R K, Baxley W A, Roubin G S
Department of Pathology, University of Alabama, Birmingham 35294.
J Am Coll Cardiol. 1992 Feb;19(2):372-81. doi: 10.1016/0735-1097(92)90494-8.
The morphologic changes in atherosclerotic coronary arteries and saphenous vein bypass grafts after placement of a balloon-expandable flexible coil stent (Cook) are described. In each case, the vessels were patent despite morphologic evidence of injury and dissection in the vessel wall. The stented region was reendothelialized and the tissue overlying the stent wires consisted primarily of smooth muscle cells. There was minimal inflammatory reaction to the stent wires. These findings suggest that the balloon-expandable flexible coil stent can effectively maintain vessel patency even in the setting of postangioplasty lumen disruption. In addition, the vessels tolerate the metal prosthesis with little evidence of tissue inflammatory reaction.
描述了放置球囊可扩张柔性线圈支架（库克公司）后，动脉粥样硬化冠状动脉和大隐静脉旁路移植血管的形态学变化。在每种情况下，尽管血管壁有损伤和夹层的形态学证据，但血管仍保持通畅。支架置入区域重新内皮化，支架丝上方的组织主要由平滑肌细胞组成。对支架丝的炎症反应极小。这些发现表明，即使在血管成形术后管腔破裂的情况下，球囊可扩张柔性线圈支架也能有效地维持血管通畅。此外，血管对金属假体耐受性良好，几乎没有组织炎症反应的迹象。
