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Synthesis, stability, and biological evaluation of water-soluble prodrugs of a new echinocandin lipopeptide. Discovery of a potential clinical agent for the treatment of systemic candidiasis and Pneumocystis carinii pneumonia (PCP).

作者信息

Balkovec J M, Black R M, Hammond M L, Heck J V, Zambias R A, Abruzzo G, Bartizal K, Kropp H, Trainor C, Schwartz R E

机构信息

Department of Synthetic Chemical Research, Merck Sharp & Dohme Research Laboratories, Rahway, New Jersey 07065.

出版信息

J Med Chem. 1992 Jan;35(1):194-8. doi: 10.1021/jm00079a027.

DOI:10.1021/jm00079a027
PMID:1732529
Abstract
摘要

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