Taylor Daniel J, Mallory Laurel J, Lichstein Kenneth L, Durrence H Heith, Riedel Brant W, Bush Andrew J
Department of Psychology, The University of North Texas, Denton, TX 76203, USA.
Sleep. 2007 Feb;30(2):213-8. doi: 10.1093/sleep/30.2.213.
Determine the comorbidity of insomnia with medical problems.
Cross-sectional and retrospective.
Community-based population of 772 men and women, aged 20 to 98 years old.
Self-report measures of sleep, health, depression, and anxiety.
People with chronic insomnia reported more of the following than did people without insomnia: heart disease (21.9% vs 9.5%), high blood pressure (43.1% vs 18.7%), neurologic disease (7.3% vs 1.2%), breathing problems (24.8% vs 5.7%), urinary problems (19.7% vs 9.5%), chronic pain (50.4% vs 18.2%), and gastrointestinal problems (33.6% vs 9.2%). Conversely, people with the following medical problems reported more chronic insomnia than did those without those medical problems: heart disease (44.1% vs 22.8%), cancer (41.4% vs 24.6%), high blood pressure (44.0% vs 19.3%), neurologic disease (66.7% vs 24.3%), breathing problems (59.6% vs 21.4%), urinary problems (41.5% vs 23.3%), chronic pain (48.6% vs 17.2%), and gastrointestinal problems (55.4% vs 20.0%). When all medical problems were considered together, only patients with high blood pressure, breathing problems, urinary problems, chronic pain, and gastrointestinal problems continued to have statistically higher levels of insomnia than those without these medical disorders.
This study demonstrates significant overlap between insomnia and multiple medical problems. Some research has shown it is possible to treat insomnia that is comorbid with select psychiatric (depression) and medical (eg, pain and cancer) disorders, which in turn increases the quality of life and functioning of these patients. The efficacy of treating insomnia in many of the above comorbid disorders has not been tested, indicating a need for future treatment research.
确定失眠与医学问题的共病情况。
横断面研究和回顾性研究。
基于社区的772名男性和女性，年龄在20至98岁之间。
睡眠、健康、抑郁和焦虑的自我报告测量。
慢性失眠患者报告的以下疾病比无失眠者更多：心脏病（21.9%对9.5%）、高血压（43.1%对18.7%）、神经系统疾病（7.3%对1.2%）、呼吸问题（24.8%对5.7%）、泌尿系统问题（19.7%对9.5%）、慢性疼痛（50.4%对18.2%）以及胃肠道问题（33.6%对9.2%）。相反，患有以下医学问题的人报告的慢性失眠比无这些医学问题的人更多：心脏病（44.1%对22.8%）、癌症（41.4%对24.6%）、高血压（44.0%对19.3%）、神经系统疾病（66.7%对24.3%）、呼吸问题（59.6%对21.4%）、泌尿系统问题（41.5%对23.3%）、慢性疼痛（48.6%对17.2%）以及胃肠道问题（55.4%对20.0%）。当综合考虑所有医学问题时，只有高血压、呼吸问题、泌尿系统问题、慢性疼痛和胃肠道问题的患者失眠水平在统计学上仍显著高于无这些疾病的患者。
本研究表明失眠与多种医学问题之间存在显著重叠。一些研究表明，治疗与特定精神疾病（抑郁症）和医学疾病（如疼痛和癌症）共病的失眠是可能的，这反过来会提高这些患者的生活质量和功能。在上述许多共病疾病中治疗失眠的疗效尚未得到测试，这表明未来需要进行治疗研究。
