Ouseph Madhu Micheal, Sharan Gautam Kumar, Sharma Prashant, Rathi Arun Kumar, Shyama Jain, Singh Kishore, Bahadur Anil Kumar
Departments of Radiotherapy, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Acta Cytol. 2007 Jan-Feb;51(1):102-6. doi: 10.1159/000325695.
Osteosarcomas, despite their aggressive nature and propensity to metastasize, only rarely give rise to skin deposits.
We report a case of a femoral osteosarcoma in which cutaneous scalp and neck metastases developed 3 years after treatment of the primary disease. Fine needle aspiration was pivotal in diagnosing the secondary disease.
Only 8 instances of cutaneous metastases from an osteosarcoma have been previously reported. We recommend early investigation of such nodules with fine needle aspiration cytology and inclusion of multiagent chemotherapy as part of the treatment protocol in all patients with osteosarcoma.
骨肉瘤尽管具有侵袭性且易于转移，但很少引起皮肤转移灶。
我们报告一例股骨骨肉瘤病例，该病例在原发性疾病治疗3年后出现头皮和颈部皮肤转移。细针穿刺抽吸在继发性疾病的诊断中起关键作用。
先前仅报道过8例骨肉瘤皮肤转移病例。我们建议对这类结节尽早进行细针穿刺细胞学检查，并将多药化疗纳入所有骨肉瘤患者的治疗方案中。
