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怀孕意愿及其与分娩和孕产妇结局的关系。

Pregnancy intention and its relationship to birth and maternal outcomes.

作者信息

Mohllajee A P, Curtis K M, Morrow B, Marchbanks P A

机构信息

Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

出版信息

Obstet Gynecol. 2007 Mar;109(3):678-86. doi: 10.1097/01.AOG.0000255666.78427.c5.

Abstract

OBJECTIVE

To examine whether there are associations between pregnancy intention (intended, unwanted, mistimed, or ambivalent) and negative birth and maternal outcomes: low birth weight (less than 2,500 g), preterm delivery (fewer than 37 weeks), small for gestational age, premature labor, hypertension, and other maternal outcomes.

METHODS

We analyzed data from the population-based Pregnancy Risk Assessment Monitoring System, including 87,087 women who gave birth between 1996 and 1999 in 18 states. Information on pregnancy outcomes was derived from birth certificate data and a self-administered questionnaire completed postpartum. We employed SUDAAN (RTI International, Research Triangle Park, NC) for univariable and logistical regression analyses.

RESULTS

In analyses controlling for demographic and behavioral factors, women with unwanted pregnancies had an increased likelihood of preterm delivery (adjusted odds ratio [OR] 1.16, 95% confidence interval [CI] 1.01-1.33) and premature rupture of membranes (adjusted OR 1.37, 95% CI 1.01-1.85) compared with women with intended pregnancies. Women who were ambivalent toward their pregnancies had increased odds of delivering a low birth weight infant (adjusted OR 1.15, 95% CI 1.02-1.29); in contrast, women with mistimed pregnancies had a lower likelihood (adjusted OR 0.92, 95% CI 0.86-0.97).

CONCLUSION

Pregnancy intention, specifically unwanted and ambivalent, may be an indicator of increased risk for some poor birth and maternal outcomes and should be considered in interventions aimed at improving the health of the mother and child.

LEVEL OF EVIDENCE

III.

摘要

目的

探讨妊娠意愿(有意、意外、时机不当或矛盾)与不良分娩及孕产妇结局之间是否存在关联,这些结局包括低出生体重(低于2500克)、早产(少于37周)、小于胎龄儿、先兆早产、高血压及其他孕产妇结局。

方法

我们分析了基于人群的妊娠风险评估监测系统的数据,其中包括1996年至1999年间在18个州分娩的87087名妇女。妊娠结局信息来自出生证明数据和产后自行填写的问卷。我们使用SUDAAN(RTI国际公司,北卡罗来纳州三角研究园)进行单变量和逻辑回归分析。

结果

在控制人口统计学和行为因素的分析中,与有意愿妊娠的妇女相比,意外妊娠的妇女发生早产(校正比值比[OR]为1.16,95%置信区间[CI]为1.01 - 1.33)和胎膜早破(校正OR为1.37,95%CI为1.01 - 1.85)的可能性增加。对妊娠持矛盾态度的妇女分娩低出生体重婴儿的几率增加(校正OR为1.15,95%CI为1.02 - 1.29);相比之下,时机不当妊娠的妇女发生这种情况的可能性较低(校正OR为0.92,95%CI为0.86 - 0.97)。

结论

妊娠意愿,特别是意外和矛盾的妊娠意愿,可能是某些不良分娩和孕产妇结局风险增加的一个指标,在旨在改善母婴健康的干预措施中应予以考虑。

证据级别

III级。

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