Ushio Munetaka, Takeuchi Naonobu, Kikuchi Shigeru, Kaga Kimitaka
Department of Otorhinolaryngology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Auris Nasus Larynx. 2007 Dec;34(4):533-6. doi: 10.1016/j.anl.2007.01.003. Epub 2007 Feb 28.
Inflammatory pseudotumour represents benign non-specific granulation, and is uncommon in the head-and-neck region, particularly in the paranasal sinuses. We present herein the case of a 63-year-old woman with inflammatory pseudotumour of the paranasal sinuses. Physical examination and computed tomography revealed a mass in the bilateral nasal cavity and paranasal sinuses with extension to bilateral orbits. Multiple intranasal biopsies revealed marked lymphoplasmatic infiltration and myofibroblastic proliferation with hyalinisation. Systemic steroid therapy was selected and was very effective. The lesion has shown no evidence of enlargement for more than 1 year. The difficulties in establishing the clinico-pathological diagnosis and treatment are discussed.
炎性假瘤表现为良性非特异性肉芽组织，在头颈部区域并不常见，尤其是在鼻窦。我们在此报告一例63岁女性鼻窦炎性假瘤的病例。体格检查和计算机断层扫描显示双侧鼻腔和鼻窦有肿物，并延伸至双侧眼眶。多次鼻内活检显示有明显的淋巴浆细胞浸润和伴有玻璃样变的肌成纤维细胞增生。选择了全身类固醇治疗，效果非常显著。该病变在1年多的时间里没有增大的迹象。文中讨论了建立临床病理诊断和治疗的难点。
