Mirabelli Maria C, Zock Jan-Paul, Plana Estel, Antó Josep Maria, Benke Geza, Blanc Paul D, Dahlman-Höglund Anna, Jarvis Deborah L, Kromhout Hans, Lillienberg Linnéa, Norbäck Dan, Olivieri Mario, Radon Katja, Sunyer Jordi, Torén Kjell, van Sprundel Marc, Villani Simona, Kogevinas Manolis
Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona, Spain.
Occup Environ Med. 2007 Jul;64(7):474-9. doi: 10.1136/oem.2006.031203. Epub 2007 Mar 1.
The authors examined the relations between self-reported work tasks, use of cleaning products and latex glove use with new-onset asthma among nurses and other healthcare workers in the European Community Respiratory Health Survey (ECRHS II).
In a random population sample of adults from 22 European sites, 332 participants reported working in nursing and other related healthcare jobs during the nine-year ECRHS II follow-up period and responded to a supplemental questionnaire about their principal work settings, occupational tasks, products used at work and respiratory symptoms. Poisson regression models with robust error variances were used to compare the risk of new-onset asthma among healthcare workers with each exposure to that of respondents who reported professional or administrative occupations during the entire follow-up period (n = 2481).
Twenty (6%) healthcare workers and 131 (5%) members of the referent population reported new-onset asthma. Compared to the referent group, the authors observed increased risks among hospital technicians (RR 4.63; 95% CI 1.87 to 11.5) and among those using ammonia and/or bleach at work (RR 2.16; 95% CI 1.03 to 4.53).
In the ECRHS II cohort, hospital technicians and other healthcare workers experience increased risks of new-onset current asthma, possibly due to specific products used at work.
作者在欧洲共同体呼吸健康调查(ECRHS II)中,研究了护士及其他医护人员自我报告的工作任务、清洁产品使用情况和乳胶手套使用情况与新发哮喘之间的关系。
在来自22个欧洲地点的成年随机人群样本中,332名参与者报告在ECRHS II为期九年的随访期间从事护理及其他相关医疗工作,并回答了一份关于其主要工作环境、职业任务、工作中使用的产品和呼吸道症状的补充问卷。使用具有稳健误差方差的泊松回归模型,比较医护人员每次接触不同因素后新发哮喘的风险与在整个随访期间报告从事专业或行政职业的受访者(n = 2481)的风险。
20名(6%)医护人员和131名(5%)对照人群报告新发哮喘。与对照组相比,作者观察到医院技术人员(相对风险4.63;95%置信区间1.87至11.5)以及工作中使用氨和/或漂白剂的人员(相对风险2.16;95%置信区间1.03至4.53)的风险增加。
在ECRHS II队列中,医院技术人员和其他医护人员新发当前哮喘的风险增加,可能是由于工作中使用的特定产品所致。