Raab Ulla, Schwegler Ursula, Preiss Ursula, Albrecht Michael, Fromme Hermann
Bavarian Health and Food Safety Authority, Department of Environmental Health, Veterinaerstrasse 2, 85764 Oberschleissheim, Germany.
Int J Hyg Environ Health. 2007 May;210(3-4):341-4. doi: 10.1016/j.ijheh.2007.01.033. Epub 2007 Mar 1.
For more than 20 years the Bavarian Health and Food Safety Authority has carried out breast milk analyses of persistent pesticides and selected organohalogen compounds. On the one hand, continuous monitoring of the levels of these chemicals in human breast milk shows a decreasing trend over these two decades. On the other hand, the number of samples sent to our institution for analysis has continuously decreased. Given the unreliable data on burden of environmental chemicals as well as the toxicologically outdated spectrum of analyzed substances, a new concept for the monitoring of breast milk has been developed and tested within a pilot study. We present here first results on PCDD, PCDF and dioxin-like PCB (dl-PCB) concentrations in breast milk of 43 women living in Bavaria, Germany. The average concentration of PCDD, PCDF and dl-PCB were 4.93, 4.98 and 9.92 pg WHO-TEQ/g fat, respectively. The new surveillance program (Bavarian Monitoring of Breast Milk, BAMBI) should track time trends of chemicals' concentrations in breast milk, while also monitoring new chemicals, such as PBDE or PFC, on which little or no German data exist.
20多年来，巴伐利亚州卫生与食品安全局一直在对母乳中的持久性农药和选定的有机卤素化合物进行分析。一方面，对母乳中这些化学物质含量的持续监测显示，在这二十年里呈下降趋势。另一方面，送到我们机构进行分析的样本数量持续减少。鉴于环境化学物质负担数据不可靠，以及所分析物质的毒理学谱过时，我们制定了一个母乳监测新概念，并在一项试点研究中进行了测试。我们在此展示了居住在德国巴伐利亚州的43名女性母乳中多氯二苯并对二噁英（PCDD）、多氯二苯并呋喃（PCDF）和类二噁英多氯联苯（dl-PCB）浓度的初步结果。PCDD、PCDF和dl-PCB的平均浓度分别为4.93、4.98和9.92皮克世卫组织毒性当量/克脂肪。新的监测计划（巴伐利亚母乳监测，BAMBI）应追踪母乳中化学物质浓度的时间趋势，同时监测德国几乎没有或根本没有数据的新化学物质，如多溴二苯醚（PBDE）或全氟化合物（PFC）。
