Girgis Reda E, Mathai Stephen C
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 1830 East Monument Street, 5th Floor, Baltimore, MD 21205, USA.
Clin Chest Med. 2007 Mar;28(1):219-32, x. doi: 10.1016/j.ccm.2006.11.006.
Pulmonary hypertension (PH) has long been recognized as a complication of chronic respiratory disease. Recent studies have highlighted the adverse impact PH has on the clinical course of these conditions and have cast doubt on the role of hypoxia in their pathogenesis. Clinicians should carefully consider the possibility of PH during the diagnostic evaluation of chronic respiratory disorders. The usefulness of pharmacologic therapy directed toward PH remains to be determined.
肺动脉高压(PH)长期以来一直被认为是慢性呼吸道疾病的一种并发症。最近的研究强调了PH对这些疾病临床病程的不利影响,并对缺氧在其发病机制中的作用提出了质疑。临床医生在慢性呼吸道疾病的诊断评估过程中应仔细考虑PH的可能性。针对PH的药物治疗的有效性仍有待确定。