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中国成年人室内传导障碍的患病率和发病率:开滦研究结果

Prevalence and incidence of intraventricular conduction disturbances among Chinese adults: Results from the Kailuan study.

作者信息

Wang Binhao, Wang Zhao, Yang Xiaolei, Han Xu, Yang Yiheng, Chu Huimin, Wu Shouling, Xia Yunlong

机构信息

Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Arrhythmia Center, Ningbo First Hospital, Ningbo, China.

出版信息

Front Cardiovasc Med. 2022 Sep 20;9:959781. doi: 10.3389/fcvm.2022.959781. eCollection 2022.

Abstract

OBJECTIVES

Epidemiological data on intraventricular conduction disturbances (IVCDs) are limited in the Chinese population. We aimed to investigate the prevalence and incidence of different types of IVCDs among Chinese adults.

METHODS

From June 2006 to October 2007, a total of 100,250 individuals from the Kailuan Study underwent electrocardiogram examinations. Follow-up visits were performed biennially. The prevalence and incidence of right bundle branch block (RBBB), incomplete RBBB (IRBBB), left bundle branch block (LBBB), incomplete LBBB, left anterior fascicular block (LAFB), left posterior fascicular block (LPFB) and non-specific IVCD (NIVCD) were calculated. Their association with risk factors and cardiovascular diseases was also investigated.

RESULTS

The prevalence and incidence of all IVCDs were 3.19 and 1.70%, respectively. RBBB, IRBBB, and LAFB were the IVCD types that had the highest prevalence and incidence. The prevalence (3.67% vs. 1.29%; < 0.001) and incidence (1.93% vs. 0.84%; < 0.001) of IVCDs were higher among males than among females. The prevalence and incidence of most IVCD types increased with age. IRBBB, LBBB, and LAFB were significantly associated with hypertension. LBBB and NIVCD were associated with diabetes mellitus. In addition, LBBB and LAFB were related to prior myocardial infarction.

CONCLUSION

IVCDs differ in prevalence and incidence according to sex and age group. They also show disparate associations with other cardiovascular comorbidities. These differences need to be considered in daily clinical practice.

摘要

目的

中国人群关于室内传导障碍(IVCDs)的流行病学数据有限。我们旨在调查中国成年人中不同类型IVCDs的患病率和发病率。

方法

2006年6月至2007年10月,开滦研究中的100250名个体接受了心电图检查。每两年进行一次随访。计算右束支传导阻滞(RBBB)、不完全性右束支传导阻滞(IRBBB)、左束支传导阻滞(LBBB)、不完全性左束支传导阻滞、左前分支传导阻滞(LAFB)、左后分支传导阻滞(LPFB)和非特异性室内传导障碍(NIVCD)的患病率和发病率。还调查了它们与危险因素和心血管疾病的关联。

结果

所有IVCDs的患病率和发病率分别为3.19%和1.70%。RBBB、IRBBB和LAFB是患病率和发病率最高的IVCD类型。IVCDs的患病率(3.67%对1.29%;<0.001)和发病率(1.93%对0.84%;<0.001)男性高于女性。大多数IVCD类型的患病率和发病率随年龄增加而升高。IRBBB、LBBB和LAFB与高血压显著相关。LBBB和NIVCD与糖尿病有关。此外,LBBB和LAFB与既往心肌梗死有关。

结论

IVCDs的患病率和发病率因性别和年龄组而异。它们与其他心血管合并症的关联也各不相同。在日常临床实践中需要考虑这些差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6b7/9530626/3bb95e9cbfa7/fcvm-09-959781-g001.jpg

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