Sah A P, Thornhill T S, LeBoff M S, Glowacki J
Department of Orthopedic Surgery, Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Osteoporos Int. 2007 Aug;18(8):1119-26. doi: 10.1007/s00198-007-0348-6. Epub 2007 Mar 6.
Radiographic parameters of the hip can be useful as an indication of bone mineral density at the femoral neck. Measurements available from routine hip radiographs were correlated with DXA values. Although radiographs are not a test for osteoporosis, measurements of cortical thickness provide information useful for referral for osteoporosis assessment.
Plain hip radiographs are widely used for evaluation of hip pathology in osteoarthritis. A purpose of this study was to determine whether there are relationships between radiographic parameters of bone structure and bone mineral density T-scores, as assessed by dual energy x-ray absorptiometry (DXA).
Pre-operative radiographs of 32 postmenopausal, osteoarthritic women undergoing hip arthroplasty were evaluated. Radiographic parameters including the Singh index, Dorr classification, canal-to-calcar ratio, and cortical thickness indices (CTI) were measured and compared with T-score, serum 25 hydroxyvitamin D levels, body mass index (BMI), and body weight.
The T-score at the femoral neck for type C bone was significantly lower than that of type A (p = 0.041). The CTIs were correlated positively with T-scores for anteroposterior radiographs (r = 0.5814, p = 0.0005), and for lateral radiographs (r = 0.571, p = 0.0006). A threshold for lateral CTI set at a value of < or =0.40 results in sensitivity of 0.85 and specificity of 0.79 to segregate the osteoporotic and non-osteoporotic patients.
Femurs with small radiographic cortical thickness indices had lower T-scores. Finding a radiographic hip cortical thickness index (LAT) with a value of < or =0.40 should be an alert for referral for osteoporosis evaluation and bone mineral density testing.
髋部的影像学参数可作为股骨颈骨矿物质密度的一个指标。从常规髋部X线片获得的测量值与双能X线吸收法(DXA)值相关。虽然X线片并非骨质疏松症的检测方法,但皮质厚度测量可为骨质疏松症评估的转诊提供有用信息。
普通髋部X线片广泛用于骨关节炎中髋部病变的评估。本研究的目的是确定通过双能X线吸收法(DXA)评估的骨结构影像学参数与骨矿物质密度T值之间是否存在关联。
对32名接受髋关节置换术的绝经后骨关节炎女性的术前X线片进行评估。测量包括辛格指数、多尔分类、髓腔与股骨距比值以及皮质厚度指数(CTI)等影像学参数,并与T值、血清25羟维生素D水平、体重指数(BMI)和体重进行比较。
C型骨股骨颈的T值显著低于A型(p = 0.041)。前后位X线片的CTI与T值呈正相关(r = 0.5814,p = 0.0005),侧位X线片的CTI与T值也呈正相关(r = 0.571,p = 0.0006)。将侧位CTI阈值设定为≤0.40时,区分骨质疏松症患者和非骨质疏松症患者的敏感度为0.85,特异度为0.79。
影像学皮质厚度指数小的股骨T值较低。发现髋部影像学皮质厚度指数(侧位)≤0.40时,应警惕转诊进行骨质疏松症评估和骨矿物质密度检测。