Orthopaedic Department of the Waldkliniken Eisenberg, Professorship of the University Hospital Jena, Campus Waldkliniken Eisenberg, Klosterlausnitzer Straße 81, 07607, Eisenberg, Germany.
Sci Rep. 2023 Nov 14;13(1):19886. doi: 10.1038/s41598-023-47247-w.
Osteoporosis is underdiagnosed in patients undergoing total hip arthroplasty (THA). Bone mineral density measurement by dual-energy X-ray absorptiometry (DXA) is the gold standard, but indices on plain hip radiographs also seemed to be reliable screening tools in female or Asian ethnicities in previous studies. Given the lack of knowledge about male patients and Caucasian ethnicities, this study was conducted to evaluate plane hip radiographic indices as a screening tool for osteopenia and osteoporosis in Caucasian female and also male patients before undergoing THA. A retrospective analysis of 216 elderly patients with pre-existing DXA before hip arthroplasty was performed and four indices were calculated on plain hip radiographs: Canal-Flare-Index (CFI), Canal-Calcar-Ratio (CCR), Canal-Bone-Ratio (CBR) 7 and 10 cm below the lesser trochanter. They were correlated with femoral neck DXA T-scores by Pearson's correlation and intraclass correlation coefficient, and a ROC analysis was performed. A total of 216 patients (49.5% male) were included. CBR-7 and -10 were highly correlated (p < 0.001) with femoral neck T-score in males (Pearson's correlation CBR-7 r = - 0.60, CBR-10 r = - 0.55) and females (r = - 0.74, r = - 0.77). CBR-7 and -10 also showed good diagnostic accuracy for osteoporosis in the ROC analysis in males (CBR-7: AUC = 0.75, threshold = 0.51; CBR-10: 0.63; 0.50) and females (CBR-7: AUC = 0.87, threshold = 0.55; CBR-10: 0.90; 0.54). Indices such as the Canal Bone Ratio (CBR) 7 or 10 cm below the lesser trochanter on plain hip radiographs are a good screening tool for osteopenia and osteoporosis on plain hip radiographs and can be used to initiate further diagnostics like the gold standard DXA. They differ between male and female patients.
骨质疏松症在接受全髋关节置换术 (THA) 的患者中被诊断不足。双能 X 射线吸收法 (DXA) 测量骨密度是金标准,但在之前的研究中,平片髋关节 X 线摄影的指数似乎也是女性或亚洲人种可靠的筛查工具。鉴于对男性患者和高加索人种缺乏了解,本研究旨在评估平片髋关节 X 线摄影指数作为高加索女性和男性患者接受 THA 前骨质疏松症和骨质疏松症的筛查工具。对 216 例术前存在 DXA 的老年患者进行回顾性分析,并在平片髋关节 X 线上计算 4 个指数:管腔-耀斑指数 (CFI)、管腔-骨距比 (CCR)、管腔-骨比 (CBR)7 和 10cm 以下小转子。通过 Pearson 相关和组内相关系数将其与股骨颈 DXA T 评分相关联,并进行 ROC 分析。共纳入 216 例患者(49.5%为男性)。男性(Pearson 相关 CBR-7 r=-0.60,CBR-10 r=-0.55)和女性(r=-0.74,r=-0.77)的 CBR-7 和 CBR-10 与股骨颈 T 评分高度相关。在 ROC 分析中,CBR-7 和 CBR-10 对男性(CBR-7:AUC=0.75,阈值=0.51;CBR-10:0.63;0.50)和女性(CBR-7:AUC=0.87,阈值=0.55;CBR-10:0.90;0.54)的骨质疏松症具有良好的诊断准确性。平片髋关节 X 线摄影下小转子下 7 或 10cm 的管腔骨比 (CBR) 等指数是平片髋关节 X 线摄影骨质疏松症和骨质疏松症的良好筛查工具,可用于启动进一步的诊断,如金标准 DXA。它们在男性和女性患者之间存在差异。