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使用腰椎磁共振图像的深度学习用于骨质疏松症诊断

Deep Learning for Osteoporosis Diagnosis Using Magnetic Resonance Images of Lumbar Vertebrae.

作者信息

Mousavinasab Seyed-Mohammadali, Hedyehzadeh Mohammadreza, Mousavinasab Seyed-Taha

机构信息

Department of Biomedical Engineering, Islamic Azad University Dezful Branch, Dezful, Iran.

Radiology Expert, Golestan Hospital, Jundi Shapur University of Medical Sciences of Ahwaz, Ahwaz, Iran.

出版信息

J Imaging Inform Med. 2025 Jul 15. doi: 10.1007/s10278-025-01547-x.

Abstract

This work uses T1, STIR, and T2 MRI sequences of the lumbar vertebrae and BMD measurements to identify osteoporosis using deep learning. An analysis of 1350 MRI images from 50 individuals who had simultaneous BMD and MRI scans was performed. The accuracy of a custom convolution neural network for osteoporosis categorization was assessed using deep learning. T2-weighted MRIs were most diagnostic. The suggested model outperformed T1 and STIR sequences with 88.5% accuracy, 88.9% sensitivity, and 76.1% F1-score. Modern deep learning models like GoogleNet, EfficientNet-B3, ResNet50, InceptionV3, and InceptionResNetV2 were compared to its performance. These designs performed well, but our model was more sensitive and accurate. This research shows that T2-weighted MRI is the best sequence for osteoporosis diagnosis and that deep learning overcomes BMD-based approaches by reducing ionizing radiation. These results support clinical use of deep learning with MRI for safe, accurate, and quick osteoporosis diagnosis.

摘要

这项研究使用腰椎的T1、短TI反转恢复(STIR)和T2磁共振成像(MRI)序列以及骨密度(BMD)测量,通过深度学习来识别骨质疏松症。对50名同时进行了BMD和MRI扫描的个体的1350张MRI图像进行了分析。使用深度学习评估了一个用于骨质疏松症分类的定制卷积神经网络的准确性。T2加权MRI的诊断价值最高。所提出的模型在准确性、敏感性和F1分数方面优于T1和STIR序列,准确率为88.5%,敏感性为88.9%,F1分数为76.1%。将谷歌网络(GoogleNet)、高效网络B3(EfficientNet-B3)、残差网络50(ResNet50)、初始网络V3(InceptionV3)和初始残差网络V2(InceptionResNetV2)等现代深度学习模型与该模型的性能进行了比较。这些模型表现良好,但我们的模型更敏感、更准确。这项研究表明,T2加权MRI是诊断骨质疏松症的最佳序列,并且深度学习通过减少电离辐射克服了基于BMD的方法。这些结果支持在临床上使用深度学习结合MRI进行安全、准确和快速的骨质疏松症诊断。

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