Bhatia K, Vaid A K, Rawal S, Patole K D
Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini Sector 5, Delhi 110085, India.
Singapore Med J. 2007 Mar;48(3):e77-80.
A 22-year-old man presented with complaints of gingival and skin lesions. Physical examination revealed the presence of two nodular lesions, one over the sternum, 3 cm in size, and another, on the right side of chin, 1 cm in size. There was another fleshy soft tissue deposit over the left lower gingiva, in the oral cavity. He had noticed these lesions ten days prior to his visit to the hospital. In addition, there was left testicular non-tender swelling which had been present for two months, but was not investigated. Fine-needle aspiration cytology from skin and gingival lesions was suggestive of metastatic deposits. Patient underwent left high orchidectomy, and histopathological examination was consistent with the diagnosis of pure choriocarcinoma. Although rare, cases of testicular neoplasms and especially choriocarcinoma of the testis leading to skin metastases have been reported, but case reports of choriocarcinoma of testis metastatic to gingiva have been reported exceptionally in the English literature. We report this unique case of a young man with pure choricarcinoma of testis with unusual gingival and skin metastases.
一名22岁男性因牙龈和皮肤病变前来就诊。体格检查发现有两个结节性病变,一个位于胸骨上方,大小为3厘米,另一个位于下巴右侧,大小为1厘米。口腔内左下牙龈处还有一个肉质软组织肿物。他在入院就诊前十天就注意到了这些病变。此外,左侧睾丸有非压痛性肿大,已持续两个月,但未进行检查。皮肤和牙龈病变的细针穿刺细胞学检查提示为转移性肿物。患者接受了左侧高位睾丸切除术,组织病理学检查结果与纯绒毛膜癌的诊断相符。虽然罕见,但睾丸肿瘤尤其是睾丸绒毛膜癌导致皮肤转移的病例已有报道,而睾丸绒毛膜癌转移至牙龈的病例报告在英文文献中极为罕见。我们报告了这名患有纯睾丸绒毛膜癌并伴有不寻常牙龈和皮肤转移的年轻男性的独特病例。