Department of Medical Oncology, Dr Lütfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey.
Clin Orthop Relat Res. 2010 Sep;468(9):2541-4. doi: 10.1007/s11999-009-1173-3. Epub 2009 Nov 25.
Testicular cancer, like other histopathologic types, commonly metastasizes to the lungs, liver, and brain. Spread to soft tissue, however, is rare with only four cases with seminoma reported. However, one case with metastasis of testicular immature teratoma to soft tissue was documented previously.
We report the case of a 38-year-old man with recurrent immature teratoma of the testis who presented with a painless soft tissue mass in the left thigh previously treated with standard chemotherapy. After removal of the soft tissue mass, his serum alpha-fetoprotein level had returned to the normal range.
To our knowledge, this is the second case of immature teratoma of the testis metastasized to soft tissue.
We suggest that for a man with testicular cancer who has a soft tissue mass, metastasis of soft tissue from testicular cancer and other solid malignancies should be considered in the differential diagnosis of a soft tissue mass together with primary soft tissue sarcoma.
与其他组织病理学类型一样,睾丸癌通常会转移到肺部、肝脏和大脑。然而,软组织转移较为罕见,仅有 4 例精原细胞瘤报告。然而,此前曾有一例睾丸未成熟畸胎瘤转移至软组织的病例。
我们报告了一例 38 岁男性复发性睾丸未成熟畸胎瘤患者,此前曾接受标准化疗治疗,左大腿无痛性软组织肿块。切除软组织肿块后,其血清甲胎蛋白水平恢复正常范围。
据我们所知,这是睾丸未成熟畸胎瘤转移至软组织的第二例病例。
我们建议,对于患有睾丸癌的男性,如果有软组织肿块,应在软组织肿块的鉴别诊断中考虑软组织转移来自睾丸癌和其他实体恶性肿瘤,同时也要考虑原发性软组织肉瘤。