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病例报告:睾丸未成熟畸胎瘤软组织转移:第二例报告并文献复习。

Case report: soft tissue metastasis from immature teratoma of the testis: second case report and review of the literature.

机构信息

Department of Medical Oncology, Dr Lütfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey.

出版信息

Clin Orthop Relat Res. 2010 Sep;468(9):2541-4. doi: 10.1007/s11999-009-1173-3. Epub 2009 Nov 25.

Abstract

BACKGROUND

Testicular cancer, like other histopathologic types, commonly metastasizes to the lungs, liver, and brain. Spread to soft tissue, however, is rare with only four cases with seminoma reported. However, one case with metastasis of testicular immature teratoma to soft tissue was documented previously.

CASE DESCRIPTION

We report the case of a 38-year-old man with recurrent immature teratoma of the testis who presented with a painless soft tissue mass in the left thigh previously treated with standard chemotherapy. After removal of the soft tissue mass, his serum alpha-fetoprotein level had returned to the normal range.

LITERATURE REVIEW

To our knowledge, this is the second case of immature teratoma of the testis metastasized to soft tissue.

PURPOSES AND CLINICAL RELEVANCE

We suggest that for a man with testicular cancer who has a soft tissue mass, metastasis of soft tissue from testicular cancer and other solid malignancies should be considered in the differential diagnosis of a soft tissue mass together with primary soft tissue sarcoma.

摘要

背景

与其他组织病理学类型一样,睾丸癌通常会转移到肺部、肝脏和大脑。然而,软组织转移较为罕见,仅有 4 例精原细胞瘤报告。然而,此前曾有一例睾丸未成熟畸胎瘤转移至软组织的病例。

病例描述

我们报告了一例 38 岁男性复发性睾丸未成熟畸胎瘤患者,此前曾接受标准化疗治疗,左大腿无痛性软组织肿块。切除软组织肿块后,其血清甲胎蛋白水平恢复正常范围。

文献回顾

据我们所知,这是睾丸未成熟畸胎瘤转移至软组织的第二例病例。

目的和临床相关性

我们建议,对于患有睾丸癌的男性,如果有软组织肿块,应在软组织肿块的鉴别诊断中考虑软组织转移来自睾丸癌和其他实体恶性肿瘤,同时也要考虑原发性软组织肉瘤。

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本文引用的文献

1
Choroidal metastasis from non-seminomatous germ cell tumour of the testis.
Br J Radiol. 2008 Jul;81(967):e188-90. doi: 10.1259/bjr/17386771.
2
Medical treatment of advanced testicular cancer.晚期睾丸癌的医学治疗
JAMA. 2008 Feb 13;299(6):672-84. doi: 10.1001/jama.299.6.672.
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Guidelines on testicular cancer.睾丸癌指南。
Eur Urol. 2005 Dec;48(6):885-94. doi: 10.1016/j.eururo.2005.06.019. Epub 2005 Jul 18.
9
Incidence of solitary soft-tissue metastases revealed by MR imaging.磁共振成像显示的孤立性软组织转移瘤的发生率。
AJR Am J Roentgenol. 2002 Dec;179(6):1644; author reply 1644. doi: 10.2214/ajr.179.6.1791644a.

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