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[干扰素-γ检测假阳性?]

[False-positive interferon-gamma test?].

作者信息

Priwitzer M, Unger C, Spieth F, Klittich G

机构信息

Landeshauptstadt Stuttgart, Gesundheitsamt, Stuttgart.

出版信息

Pneumologie. 2007 Mar;61(3):157-8. doi: 10.1055/s-2006-954980.

DOI:10.1055/s-2006-954980
PMID:17342575
Abstract

M. tuberculosis specific interferon-gamma tests have been established lately as an important additional instrument in the diagnosis of the latent tuberculosis infection (LTBI). In several studies these tests had a higher specificity compared to the tuberculin skin test (TST). In this report we describe the case of a woman without increased risk for LTBI and with discordant results for the interferon-gamma tests QuantiFERON-TB Gold In-Tube and T-SPOT.TB and for the TST. The findings suggest repeated false-positive results of the QuantiFERON-TB Gold In-Tube test.

摘要

结核分枝杆菌特异性干扰素-γ检测最近已成为诊断潜伏性结核感染(LTBI)的一项重要辅助手段。在多项研究中,这些检测的特异性高于结核菌素皮肤试验(TST)。在本报告中,我们描述了一名女性病例,该女性无LTBI风险增加因素,其QuantiFERON-TB Gold In-Tube检测、T-SPOT.TB检测及TST结果不一致。这些发现提示QuantiFERON-TB Gold In-Tube检测反复出现假阳性结果。

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