Rothman J E, Orci L
Program of Cellular Biochemistry and Biophysics, Rockefeller Research Laboratory, Sloan-Kettering Institute, New York, New York 10021.
Nature. 1992 Jan 30;355(6359):409-15. doi: 10.1038/355409a0.
A combination of biochemistry in animal cell-free systems and genetics in yeast is revealing the molecular machinery of the secretory pathway of eukaryotes. Transporting vesicles have a simple coat structure and employ a general mechanism for fusion that is conserved in evolution.
动物无细胞系统中的生物化学与酵母遗传学相结合，正揭示真核生物分泌途径的分子机制。运输小泡具有简单的包被结构，并采用一种在进化中保守的通用融合机制。
