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在家禽肌肉注射[4-¹⁴C]雌酮后尿液中放射性17β-雌二醇-17-β-D-葡萄糖醛酸苷和17α-雌二醇-17-β-D-葡萄糖醛酸苷的鉴定。

Identification of radioactive 17beta-estradiol-17-beta-D-glucuronide and 17alpha-estradiol-17-beta-D-glucuronide in the urine of the domestic fowl after intramuscular injection of [4-14C]estrone.

作者信息

Robinson A R, Baker S J, Common R H

出版信息

Can J Biochem. 1975 Oct;53(10):1085-8. doi: 10.1139/o75-149.

Abstract

Two previously uncharacterized radioactive estrogen conjugates, 17beta-estradiol-17-beta-D-glucuronide (3-hydroxyestra-1,3,5(10)-trien-17beta-D-glucopyranosiduronate) and 17alpha-estradiol-17beta-D-glucuronide (3-hydroxyestra-1,3,5(10)-trien-17alpha-yl-beta-D-glucopyranosiduronate), have been identified in small but significant amounts in avian urine and in a ratio of approximately 2:1 after intramuscular injection of [4-14C]estrone.

摘要

两种先前未被表征的放射性雌激素共轭物,17β-雌二醇-17-β-D-葡萄糖醛酸苷(3-羟基雌甾-1,3,5(10)-三烯-17β-D-葡萄糖吡喃糖醛酸苷)和17α-雌二醇-17β-D-葡萄糖醛酸苷(3-羟基雌甾-1,3,5(10)-三烯-17α-基-β-D-葡萄糖吡喃糖醛酸苷),已在鸟类尿液中被鉴定出,含量虽少但具有显著意义,且在肌肉注射[4-¹⁴C]雌酮后,其比例约为2:1。

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