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伴有和不伴有慢性抽动障碍的青少年强迫症

Obsessive-compulsive disorder in youth with and without a chronic tic disorder.

作者信息

Storch Eric A, Stigge-Kaufman David, Marien Wendi E, Sajid Muhammad, Jacob Marni L, Geffken Gary R, Goodman Wayne K, Murphy Tanya K

机构信息

Department of Psychiatry, University of Florida, Gainesville, Florida 32610, USA.

出版信息

Depress Anxiety. 2008;25(9):761-7. doi: 10.1002/da.20304.

Abstract

The goal of this study was to discriminate subtypes of pediatric obsessive-compulsive disorder (OCD) among youth with and without a comorbid tic disorder. Seventy-four youth (M(age)=9.7+/-2.3 years) with a principal diagnosis of OCD, with (n=46) or without (n=28) a comorbid tic disorder, were assessed with a semi-structured diagnostic interview and the Children's Yale Brown Obsessive-Compulsive Scale (CY-BOCS). The CY-BOCS Symptom Checklist was used to categorize obsessions and compulsions. Group differences were analyzed by t tests, chi(2), and discriminant function analyses. Results suggested that subjects without tics had significantly more contamination obsessions, sexual obsessions, and counting compulsions than youth with comorbid tics. Generally speaking, however, youth with and without tics had similar symptom presentations. These data suggest that pediatric OCD patients with and without comorbid tics may have some aspects of symptom presentation that differ, but generally have more OCD symptoms in common than different. Implications of these findings on clinical presentation and treatment efficacy are highlighted.

摘要

本研究的目的是区分患有和未患有共病抽动障碍的青少年中的小儿强迫症(OCD)亚型。74名主要诊断为强迫症的青少年(平均年龄=9.7±2.3岁),其中46名患有共病抽动障碍,28名未患有共病抽动障碍,接受了半结构化诊断访谈和儿童耶鲁布朗强迫症量表(CY-BOCS)评估。CY-BOCS症状清单用于对强迫观念和强迫行为进行分类。通过t检验、卡方检验和判别函数分析来分析组间差异。结果表明,没有抽动症状的受试者比患有共病抽动障碍的青少年有更多的污染强迫观念、性强迫观念和计数强迫行为。然而,总体而言,有和没有抽动症状的青少年有相似的症状表现。这些数据表明,患有和未患有共病抽动障碍的小儿强迫症患者可能在症状表现的某些方面存在差异,但总体上强迫症症状的共同点多于不同点。强调了这些发现对临床表现和治疗效果的影响。

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