Belmonte Matthew K, Mazziotta John C, Minshew Nancy J, Evans Alan C, Courchesne Eric, Dager Stephen R, Bookheimer Susan Y, Aylward Elizabeth H, Amaral David G, Cantor Rita M, Chugani Diane C, Dale Anders M, Davatzikos Christos, Gerig Guido, Herbert Martha R, Lainhart Janet E, Murphy Declan G, Piven Joseph, Reiss Allan L, Schultz Robert T, Zeffiro Thomas A, Levi-Pearl Susan, Lajonchere Clara, Colamarino Sophia A
Department of Human Development, Cornell University, Martha Van Rensselaer Hall, Ithaca, NY 14853-4401, USA.
J Autism Dev Disord. 2008 Jan;38(1):2-13. doi: 10.1007/s10803-006-0352-2. Epub 2007 Mar 9.
Data sharing in autism neuroimaging presents scientific, technical, and social obstacles. We outline the desiderata for a data-sharing scheme that combines imaging with other measures of phenotype and with genetics, defines requirements for comparability of derived data and recommendations for raw data, outlines a core protocol including multispectral structural and diffusion-tensor imaging and optional extensions, provides for the collection of prospective, confound-free normative data, and extends sharing and collaborative development not only to data but to the analytical tools and methods applied to these data. A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on.
自闭症神经影像学中的数据共享存在科学、技术和社会障碍。我们概述了一种数据共享方案的需求，该方案将成像与其他表型测量和遗传学相结合，定义了衍生数据可比性的要求以及原始数据的建议，概述了一个核心协议，包括多光谱结构和扩散张量成像以及可选扩展，规定了前瞻性、无混杂因素的规范数据的收集，并不仅将共享和协作开发扩展到数据，还扩展到应用于这些数据的分析工具和方法。这些要求中的一个主题是，需要在为各个实验室提供共同标准以供其借鉴的同时，保留各个实验室内部的创新方法和冒险精神。
