高功能自闭症儿童的神经影像学表现正常率。
Normal rates of neuroradiological findings in children with high functioning autism.
机构信息
Laboratory of Neurocognitive and Imaging Research, Center for Autism and Related Disorders, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21211, USA.
出版信息
J Autism Dev Disord. 2012 Aug;42(8):1662-70. doi: 10.1007/s10803-011-1407-6.
Magnetic resonance imaging (MRI) has been used to analyze highly specific volumetric and morphological features of the brains of individuals with autism spectrum disorder (ASD). To date, there are few comprehensive studies examining the prevalence of neuroradiologic findings seen on routine MRI scans in children with ASD. This study examined the prevalence of neuroradiologic findings in children with high functioning ASD, and compared these rates to those in children with Attention-Deficit/Hyperactivity Disorder (ADHD) and children who are typically developing (TD). Results showed that approximately 90% of children had normal MRI scans. There was no significant effect of diagnosis on the total number of neuroradiological findings or the number of specific brain findings. Implications and future research directions are discussed.
磁共振成像（MRI）已被用于分析自闭症谱系障碍（ASD）个体大脑的高度特异性容积和形态特征。迄今为止，很少有全面的研究检查自闭症儿童常规 MRI 扫描中可见的神经影像学发现的患病率。本研究检查了高功能自闭症儿童的神经影像学发现的患病率，并将这些比率与注意力缺陷/多动障碍（ADHD）儿童和典型发育（TD）儿童进行了比较。结果表明，约 90%的儿童的 MRI 扫描正常。诊断对神经影像学发现的总数或特定脑发现的数量没有显著影响。讨论了其意义和未来的研究方向。
Zotero 插件