Pizzo Giuseppe, Licata Maria Ester, La Cara Monica, Pizzo Ignazio, Guiglia Rosario, Melilli Dario
Department of Oral Sciences, University of Palermo, Via del Vespro 129, 90127 Palermo, Italy.
J Dent. 2007 Jun;35(6):503-8. doi: 10.1016/j.jdent.2007.01.008. Epub 2007 Mar 9.
Sugar-free chewing gum has been claimed to be a useful means of reducing dental plaque accumulation. The incorporation of additives, such as enzymes, abrasives and divalent metal ions, into gum formulations might improve their antiplaque activity, particularly at the buccal and lingual surfaces of the teeth.
The aim of this study was to investigate the plaque inhibitory effects of three sugar-free chewing gums each containing lactoperoxidase (LP), micro granules of silicon dioxide (SD), and zinc gluconate (ZG).
The study was an observer-masked, randomized cross-over design balanced for carryover effects, involving 12 healthy volunteers in a 4-day plaque regrowth model. An additive-free (AF) gum served as positive/negative control for occlusal and smooth surfaces, respectively. On day 1, subjects received professional prophylaxis, suspended oral hygiene measures, and commenced chewing their allocated product. Gum chewing was one piece chewed for 30min 4 times a day. On day 5, subjects were scored for disclosed plaque.
There were no significant differences in antiplaque activity of the gums tested, neither for the smooth nor for the occlusal surfaces (P=0.447 and P=0.418, respectively). Similar results were obtained for the anterior and posterior sites of smooth surfaces (P>0.05), and for the lower and upper sites of occlusal surfaces (P=0.451 and P=0.53, respectively).
These findings suggest that the chewing gums containing LP, SD and ZG would provide no plaque inhibitory effects on smooth surfaces. The gums containing these additives, therefore, should not be recommended as adjuncts to mechanical oral hygiene.
无糖口香糖被认为是减少牙菌斑积聚的一种有效手段。在口香糖配方中加入添加剂,如酶、磨料和二价金属离子,可能会提高其防龋活性,特别是在牙齿的颊面和舌面。
本研究旨在调查三种分别含有乳过氧化物酶(LP)、二氧化硅微粒(SD)和葡萄糖酸锌(ZG)的无糖口香糖对牙菌斑的抑制作用。
本研究采用观察者盲法、随机交叉设计,并对残留效应进行平衡,在一个为期4天的牙菌斑再生长模型中纳入了12名健康志愿者。一种无添加剂(AF)口香糖分别作为咬合面和平滑面的阳性/阴性对照。在第1天,受试者接受专业口腔清洁,暂停口腔卫生措施,并开始咀嚼分配给他们的产品。每天咀嚼口香糖4次,每次1片,持续30分钟。在第5天,对受试者的牙菌斑进行评分。
所测试的口香糖在防龋活性方面没有显著差异,无论是平滑面还是咬合面(P分别为0.447和0.418)。平滑面前后部位(P>0.05)以及咬合面上下部位(P分别为0.451和0.53)也得到了类似的结果。
这些发现表明,含有LP、SD和ZG的口香糖对平滑面没有牙菌斑抑制作用。因此,不应推荐含有这些添加剂的口香糖作为机械口腔卫生的辅助用品。