Siebenhaar F, Weller K, Mlynek A, Magerl M, Altrichter S, Vieira Dos Santos R, Maurer M, Zuberbier T
Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Clin Exp Dermatol. 2007 May;32(3):241-5. doi: 10.1111/j.1365-2230.2007.02376.x. Epub 2007 Mar 13.
Acquired cold urticaria (ACU) is a frequent subtype of physical urticaria that is caused by the release of proinflammatory mast cell mediators after cold exposure. Although the underlying causes of ACU still remain to be clarified in detail, a wide range of diseases has been reported to be associated with ACU. This review gives an overview of the clinical picture, the differential diagnoses, diagnostic tests and the aetiology of ACU, and summarizes current and novel therapeutic options based on the current literature.
获得性寒冷性荨麻疹（ACU）是物理性荨麻疹中常见的一种亚型，由寒冷暴露后促炎性肥大细胞介质的释放所引起。尽管ACU的潜在病因仍有待详细阐明，但已有广泛的疾病被报道与ACU相关。本综述概述了ACU的临床表现、鉴别诊断、诊断测试及病因，并根据当前文献总结了现有的和新的治疗选择。
